Therapeutics

Cost-effectiveness of total knee replacement in addition to non-surgical treatment: a 2-year outcome from a randomised trial in secondary care in Denmark
Søren Thorgaard Skou, Ewa Roos, Mogens Laursen, Lars Arendt-Nielsen, Sten Rasmussen, Ole Simonsen, Rikke Ibsen, Arendse T Larsen, Jakob Kjellberg

BMJ Open Jan 2020, 10 (1) e033495; DOI: 10.1136/bmjopen-2019-033495
Best emollients for eczema (BEE) – comparing four types of emollients in children with eczema: protocol for randomised trial and nested qualitative study
Matthew J Ridd, Sian Wells, Louisa Edwards, Miriam Santer, Stephanie MacNeill, Emily Sanderson, Eileen Sutton, Alison R G Shaw, Jonathan Banks, Kirsty Garfield, Amanda Roberts, Tiffany J Barrett, Helen Baxter, Jodi Taylor, J Athene Lane, Alastair D Hay, Hywel C Williams, Kim Suzanne Thomas

BMJ Open Nov 2019, 9 (11) e033387; DOI: 10.1136/bmjopen-2019-033387
The CoDiNOS trial protocol: an international randomised controlled trial of intravenous sildenafil versus inhaled nitric oxide for the treatment of pulmonary hypertension in neonates with congenital diaphragmatic hernia
Suzan Cochius-den Otter, Thomas Schaible, Anne Greenough, Arno van Heijst, Neil Patel, Karel Allegaert, Joost van Rosmalen, Dick Tibboel

BMJ Open Nov 2019, 9 (11) e032122; DOI: 10.1136/bmjopen-2019-032122
What causes prescribing errors in children? Scoping review
Richard L Conn, Orla Kearney, Mary P Tully, Michael D Shields, Tim Dornan

BMJ Open Aug 2019, 9 (8) e028680; DOI: 10.1136/bmjopen-2018-028680
Rehabilitation for balance impairment in patients after stroke: a protocol of a systematic review and network meta-analysis
Juan Li, Dongling Zhong, Jing Ye, Mingxing He, Xicen Liu, Hui Zheng, Rongjiang Jin, Shao-lan Zhang

BMJ Open Jul 2019, 9 (7) e026844; DOI: 10.1136/bmjopen-2018-026844
Protect-me: a parallel-group, triple blinded, placebo-controlled randomised clinical trial protocol assessing antenatal maternal melatonin supplementation for fetal neuroprotection in early-onset fetal growth restriction
Kirsten R Palmer, Joanne C Mockler, Miranda L Davies-Tuck, Suzanne L Miller, Stacy K Goergen, Michael C Fahey, Peter J Anderson, Katie M Groom, Euan M Wallace

BMJ Open Jun 2019, 9 (6) e028243; DOI: 10.1136/bmjopen-2018-028243
Effectiveness of antitussives, anticholinergics or honey versus usual care in adults with uncomplicated acute bronchitis: a study protocol of an open randomised clinical trial in primary care
Josep M Cots, Ana Moragas, Ana García-Sangenís, Rosa Morros, Ainhoa Gomez-Lumbreras, Dan Ouchi, Ramon Monfà, Helena Pera, Jesus Pujol, Carolina Bayona, Mariam de la Poza-Abad, Carl Llor

BMJ Open May 2019, 9 (5) e028159; DOI: 10.1136/bmjopen-2018-028159
ETS-related gene (ERG) expression as a predictor of oncological outcomes in patients with high-grade prostate cancer treated with primary androgen deprivation therapy: a cohort study
Mark Rezk, Ashish Chandra, Daniel Addis, Henrik Møller, Mina Youssef, Prokar Dasgupta, Hide Yamamoto

BMJ Open Mar 2019, 9 (3) e025161; DOI: 10.1136/bmjopen-2018-025161
Trends in comparative efficacy and safety of malaria control interventions for maternal and child health outcomes in Africa: a study protocol for a Bayesian network meta-regression exploring the effect of HIV and malaria endemicity spectrum
Floriano Amimo, Troy D Moon, Anthony Magit, Jahit Sacarlal, Ben Lambert, Shuhei Nomura

BMJ Open Feb 2019, 9 (2) e024313; DOI: 10.1136/bmjopen-2018-024313
Comparative safety of the sodium glucose co-transporter 2 (SGLT2) inhibitors: a systematic review and meta-analysis
Jennifer R Donnan, Catherine A Grandy, Eugene Chibrikov, Carlo A Marra, Kris Aubrey-Bassler, Karissa Johnston, Michelle Swab, Jenna Hache, Daniel Curnew, Hai Nguyen, John-Michael Gamble

BMJ Open Jan 2019, 9 (1) e022577; DOI: 10.1136/bmjopen-2018-022577

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