Autophagy, the starvation-induced degradation of bulky cytosolic components, is up-
regulated in mammalian cells when nutrient supplies are limited. Although mammalian …

A thorough investigation of membranes as well as their transport and material properties is a
key to understanding the governing principles and unresolved issues of membrane …

CONTEXT: Family planning services are frequently used and important services for
American women, yet little is known about their quality. Service quality has important …

Endostatin, a fragment of collagen XVIII, is a potent anti-angiogenic protein, but the
molecular mechanism of its action is not yet clear. We examined the effects of endostatin on …

New therapeutic strategies are needed to combat the tuberculosis pandemic and the spread
of multidrug-resistant (MDR) and extensively drug-resistant (XDR) forms of the disease …

Here we report the inhibition of cellular invasion by a recombinant mouse endostatin and the
possible mechanism of the inhibition. Endostatin significantly reduced endothelial as well as …

Sphingosine 1-phosphate (S1P) is a bioactive sphingolipid metabolite abundantly stored in
platelets and released upon platelet activation. Recently, S1P has been postulated for its …

GPR119 belongs to the G protein‐coupled receptor family and exhibits dual modes of action
upon ligand‐dependent activation: pancreatic secretion of insulin in a glucose‐dependent …

abstract ULK1 (unc-51 like autophagy activating kinase 1), the key mediator of MTORC1
signaling to autophagy, regulates early stages of autophagosome formation in response to …

Cucumis sativus (cucumber) was tested to assess an ecotoxicity in soils contaminated by the
heavy metals copper (Cu), cadmium (Cd), and lead (Pb) separately and in combinations …