LncRNA-mediated regulation of cell signaling in cancer
To date, a large number of long non-coding RNAs (lncRNAs) have been recently discovered
through functional genomics studies. Importantly, lncRNAs have been shown, in many …
through functional genomics studies. Importantly, lncRNAs have been shown, in many …
[HTML][HTML] Emerging roles of lncRNAs in the post-transcriptional regulation in cancer
RZ He, DX Luo, YY Mo - Genes & diseases, 2019 - Elsevier
Accumulating evidence indicates that long non-coding RNAs (lncRNAs) can play a pivotal
role in regulation of diverse cellular processes. In particular, lncRNAs can serve as master …
role in regulation of diverse cellular processes. In particular, lncRNAs can serve as master …
Role of microRNAs in breast cancer
R Singh, YY Mo - Cancer biology & therapy, 2013 - Taylor & Francis
MicroRNAs (miRNAs) are a class of post-transcriptional gene regulators with critical
functions in normal cellular processes as well as disease processes. They are small …
functions in normal cellular processes as well as disease processes. They are small …
[HTML][HTML] MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
MicroRNAs (miRNAs) are a class of naturally occurring small non-coding RNAs that target
protein-coding mRNAs at the post-transcriptional level. Our previous studies suggest that mir …
protein-coding mRNAs at the post-transcriptional level. Our previous studies suggest that mir …
[HTML][HTML] MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1)
MicroRNAs are small noncoding RNA molecules that control expression of target genes. Our
previous studies show that mir-21 is overexpressed in tumor tissues compared with the …
previous studies show that mir-21 is overexpressed in tumor tissues compared with the …
p53 represses c-Myc through induction of the tumor suppressor miR-145
The tumor suppressor p53 negatively regulates a number of genes, including the proto-
oncogene c-Myc, in addition to activating many other genes. One mechanism of the p53 …
oncogene c-Myc, in addition to activating many other genes. One mechanism of the p53 …
Effect of piperacillin-tazobactam vs meropenem on 30-day mortality for patients with E coli or Klebsiella pneumoniae bloodstream infection and ceftriaxone resistance …
Importance Extended-spectrum β-lactamases mediate resistance to third-generation
cephalosporins (eg, ceftriaxone) inEscherichia coliandKlebsiella pneumoniae. Significant …
cephalosporins (eg, ceftriaxone) inEscherichia coliandKlebsiella pneumoniae. Significant …
MicroRNA-145 suppresses cell invasion and metastasis by directly targeting mucin 1
M Sachdeva, YY Mo - Cancer research, 2010 - AACR
MicroRNAs are important gene regulators that could play a profound role in tumorigenesis.
Our previous studies indicate that miR-145 is a tumor suppressor capable of inhibiting tumor …
Our previous studies indicate that miR-145 is a tumor suppressor capable of inhibiting tumor …
Fatty acid synthase gene is up-regulated by hypoxia via activation of Akt and sterol regulatory element binding protein-1
E Furuta, SK Pai, R Zhan, S Bandyopadhyay… - Cancer research, 2008 - AACR
The fatty acid synthase (FAS) gene is significantly up-regulated in various types of cancers,
and blocking the FAS expression results in apoptosis of tumor cells. Therefore, FAS is …
and blocking the FAS expression results in apoptosis of tumor cells. Therefore, FAS is …
LncRNA loc285194 is a p53-regulated tumor suppressor
Protein-coding genes account for only a small part of the human genome, whereas the vast
majority of transcripts make up the non-coding RNAs including long non-coding RNAs …
majority of transcripts make up the non-coding RNAs including long non-coding RNAs …