Tip60: connecting chromatin to DNA damage signaling
Y Sun, X Jiang, BD Price - Cell cycle, 2010 - Taylor & Francis
Cells are constantly exposed to genotoxic events that can damage DNA. To counter this,
cells have evolved a series of highly conserved DNA repair pathways to maintain genomic …
cells have evolved a series of highly conserved DNA repair pathways to maintain genomic …
[HTML][HTML] Exosomes in pathogen infections: a bridge to deliver molecules and link functions
W Zhang, X Jiang, J Bao, Y Wang, H Liu… - Frontiers in …, 2018 - frontiersin.org
Exosomes are extracellular vesicles derived from cell endocytosis which act as transmitters
between cells. They are composed of proteins, lipids, and RNAs through which they …
between cells. They are composed of proteins, lipids, and RNAs through which they …
[HTML][HTML] Mesenchymal stem cell-derived exosome: A tumor regulator and carrier for targeted tumor therapy
F Zhang, J Guo, Z Zhang, Y Qian, G Wang, M Duan… - Cancer letters, 2022 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent stromal cells that have the ability to
differentiate into multiple cell types. Several studies have shown that exosomes secreted by …
differentiate into multiple cell types. Several studies have shown that exosomes secreted by …
A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM
Y Sun, X Jiang, S Chen… - Proceedings of the …, 2005 - National Acad Sciences
The ataxia telangiectasia mutant (ATM) protein kinase regulates the cell's response to DNA
damage through the phosphorylation of proteins involved in cell-cycle checkpoints and DNA …
damage through the phosphorylation of proteins involved in cell-cycle checkpoints and DNA …
Ecotoxicity and genotoxicity of polystyrene microplastics on higher plant Vicia faba
X Jiang, H Chen, Y Liao, Z Ye, M Li, G Klobučar - Environmental Pollution, 2019 - Elsevier
Nano-and microplastics have been widely spread in environmental matrices, especially in
marine and terrestrial systems. In this study, higher plant Vicia faba root tips were exposed to …
marine and terrestrial systems. In this study, higher plant Vicia faba root tips were exposed to …
The activation of MAPK in melanoma cells resistant to BRAF inhibition promotes PD-L1 expression that is reversible by MEK and PI3K inhibition
X Jiang, J Zhou, A Giobbie-Hurder, J Wargo… - Clinical cancer …, 2013 - AACR
Abstract Purpose: Selective BRAF inhibition (BRAFi) provides a paradigm shift for
melanoma treatment. The duration of benefit is typically limited before resistance develops …
melanoma treatment. The duration of benefit is typically limited before resistance develops …
Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60
Y Sun, X Jiang, Y Xu, MK Ayrapetov, LA Moreau… - Nature cell …, 2009 - nature.com
DNA double-strand break (DSB) repair involves complex interactions between chromatin
and repair proteins, including Tip60, a tumour suppressor. Tip60 is an acetyltransferase that …
and repair proteins, including Tip60, a tumour suppressor. Tip60 is an acetyltransferase that …
[HTML][HTML] Predicting treatment response from longitudinal images using multi-task deep learning
Radiographic imaging is routinely used to evaluate treatment response in solid tumors.
Current imaging response metrics do not reliably predict the underlying biological response …
Current imaging response metrics do not reliably predict the underlying biological response …
Toxicological effects of polystyrene microplastics on earthworm (Eisenia fetida)
X Jiang, Y Chang, T Zhang, Y Qiao, G Klobučar… - Environmental …, 2020 - Elsevier
Microplastics are plastic fragments of particle sizes less than 5 mm, which are widely
distributed in marine and terrestrial environments. In this study, earthworms Eisenia fetida …
distributed in marine and terrestrial environments. In this study, earthworms Eisenia fetida …
[HTML][HTML] Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation
Y Sun, X Jiang, S Chen, BD Price - FEBS letters, 2006 - Elsevier
Histone acetyltransferases (HATs) regulate transcription, chromatin structure and DNA
repair. Here, we utilized a novel HAT inhibitor, anacardic acid, to examine the role of HATs …
repair. Here, we utilized a novel HAT inhibitor, anacardic acid, to examine the role of HATs …