CHD8 is an ATP-dependent chromatin remodeling factor that regulates β-catenin target genes
BA Thompson, V Tremblay, G Lin… - Molecular and cellular …, 2008 - Taylor & Francis
ATP-dependent chromatin remodeling by the CHD family of proteins plays an important role
in the regulation of gene transcription. Here we report that full-length CHD8 interacts directly …
in the regulation of gene transcription. Here we report that full-length CHD8 interacts directly …
[HTML][HTML] Krüppel-like factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension
A Courboulin, VL Tremblay, M Barrier, J Meloche… - Respiratory …, 2011 - Springer
Background Pulmonary arterial hypertension (PAH) is a vascular remodeling disease
characterized by enhanced proliferation of pulmonary artery smooth muscle cell (PASMC) …
characterized by enhanced proliferation of pulmonary artery smooth muscle cell (PASMC) …
Proteomic analyses of the SMYD family interactomes identify HSP90 as a novel target for SMYD2
M Abu-Farha, S Lanouette, F Elisma… - Journal of molecular …, 2011 - academic.oup.com
Abstract The SMYD (SET and MYND domain) family of lysine methyltransferases (KMTs)
plays pivotal roles in various cellular processes, including gene expression regulation and …
plays pivotal roles in various cellular processes, including gene expression regulation and …
UTX inhibition as selective epigenetic therapy against TAL1-driven T-cell acute lymphoblastic leukemia
T-cell acute lymphoblastic leukemia (T-ALL) is a heterogeneous group of hematological
tumors composed of distinct subtypes that vary in their genetic abnormalities, gene …
tumors composed of distinct subtypes that vary in their genetic abnormalities, gene …
[PDF][PDF] Structural and biochemical insights into MLL1 core complex assembly
V Avdic, P Zhang, S Lanouette, A Groulx, V Tremblay… - Structure, 2011 - cell.com
Histone H3 Lys-4 methylation is predominantly catalyzed by a family of methyltransferases
whose enzymatic activity depends on their interaction with a three-subunit complex …
whose enzymatic activity depends on their interaction with a three-subunit complex …
[PDF][PDF] Acetylation of PCNA sliding surface by Eco1 promotes genome stability through homologous recombination
During DNA replication, proliferating cell nuclear antigen (PCNA) adopts a ring-shaped
structure to promote processive DNA synthesis, acting as a sliding clamp for polymerases …
structure to promote processive DNA synthesis, acting as a sliding clamp for polymerases …
Molecular basis for DPY-30 association to COMPASS-like and NURF complexes
V Tremblay, P Zhang, CP Chaturvedi, J Thornton… - Structure, 2014 - cell.com
DPY-30 is a subunit of mammalian COMPASS-like complexes (complex of proteins
associated with Set1) and regulates global histone H3 Lys-4 trimethylation. Here we report …
associated with Set1) and regulates global histone H3 Lys-4 trimethylation. Here we report …
Crystal structure of the trithorax group protein ASH2L reveals a forkhead-like DNA binding domain
S Sarvan, V Avdic, V Tremblay, CP Chaturvedi… - Nature structural & …, 2011 - nature.com
Absent, small or homeotic discs–like 2 (ASH2L) is a trithorax group (TrxG) protein and a
regulatory subunit of the SET1 family of lysine methyltransferases. Here we report that …
regulatory subunit of the SET1 family of lysine methyltransferases. Here we report that …
Brighter red fluorescent proteins by rational design of triple-decker motif
AT Pandelieva, MJ Baran, GF Calderini… - ACS chemical …, 2016 - ACS Publications
Red fluorescent proteins (RFPs) are used extensively in chemical biology research as
fluorophores for live cell imaging, as partners in FRET pairs, and as signal transducers in …
fluorophores for live cell imaging, as partners in FRET pairs, and as signal transducers in …
Cardiac implantable electronic device infection: detailed analysis of cost implications
E Gitenay, F Molin, S Blais, V Tremblay… - Canadian Journal of …, 2018 - Elsevier
Background Infections of cardiac implantable electronic devices (CIED) are associated with
significant morbidity and mortality. Despite many preventive measures, this condition is …
significant morbidity and mortality. Despite many preventive measures, this condition is …