Frontotemporal dementia with the C9ORF72 hexanucleotide repeat expansion: clinical, neuroanatomical and neuropathological features
An expanded hexanucleotide repeat in the C9ORF72 gene has recently been identified as a
major cause of familial frontotemporal lobar degeneration and motor neuron disease …
major cause of familial frontotemporal lobar degeneration and motor neuron disease …
Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease
Introduction The genetics underlying posterior cortical atrophy (PCA), typically a rare variant
of Alzheimer's disease (AD), remain uncertain. Methods We genotyped 302 PCA patients …
of Alzheimer's disease (AD), remain uncertain. Methods We genotyped 302 PCA patients …
Shining a light on posterior cortical atrophy
Posterior cortical atrophy (PCA) is a clinicoradiologic syndrome characterized by
progressive decline in visual processing skills, relatively intact memory and language in the …
progressive decline in visual processing skills, relatively intact memory and language in the …
Successful use of “Choice Architecture” and “Nudge Theory” in a quality improvement initiative of analgesia administration after Caesarean section
T Shakespeare, M Fehlberg, T Slejko… - Journal of evaluation …, 2019 - Wiley Online Library
Background Regular, routine, multimodal analgesia provides better pain relief following
Caesarean section than reliance on “as required” opiate dosing. This quality improvement …
Caesarean section than reliance on “as required” opiate dosing. This quality improvement …
Qualitative, exploratory pilot study to investigate how people living with posterior cortical atrophy, their carers and clinicians experience tests used to assess vision
Objectives To investigate the experiences and views of people living with posterior cortical
atrophy (PCA), their family carers and healthcare professionals of vision assessment tests …
atrophy (PCA), their family carers and healthcare professionals of vision assessment tests …
Posterior cortical atrophy: advice for diagnosis and implications for management
The clinical presentation of Alzheimer's disease (AD) is heterogeneous, especially in
individuals with an early age at onset, where the presenting symptoms may be language …
individuals with an early age at onset, where the presenting symptoms may be language …
Genetic risk factors for posterior cortical atrophy
Genetic risk factors for posterior cortical atrophy × Close The Infona portal uses cookies, ie
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[CITATION][C] O5‐05‐02: Eye tracking in posterior cortical atrophy: A new insight into the visual syndrome
S Crutch, T Shakespeare - Alzheimer's & Dementia, 2012 - Wiley Online Library
Background Visual disorientation is a common and disabling symptom in Posterior Cortical
Atrophy (PCA). However few quantitative studies of point localisation skills have been …
Atrophy (PCA). However few quantitative studies of point localisation skills have been …
[CITATION][C] P2‐084: Retinal nerve fibre layer (RNFL) thinning in genetic ftd
KM Dick, TJ Shakespeare, SJ Crutch… - Alzheimer's & …, 2015 - Wiley Online Library
Background Retinal abnormalities have been found in a number of different
neurodegenerative diseases. A recent study highlighted the presence of retinal …
neurodegenerative diseases. A recent study highlighted the presence of retinal …
[CITATION][C] P1‐473: Face, scene and object perception in posterior cortical atrophy
T Shakespeare, S Crutch… - Alzheimer's & Dementia, 2011 - Wiley Online Library
Background Posterior cortical atrophy (PCA) is a degenerative condition characterised by
progressive visual dysfunction and atrophy of the parietal and occipital lobes, most …
progressive visual dysfunction and atrophy of the parietal and occipital lobes, most …