Cardiovascular interventions have achieved a level of excellence, with many outstanding
advanced techniques and results. The mission of the Japanese Association of …

While primary percutaneous coronary intervention (PCI) has significantly contributed to
improve the mortality in patients with ST segment elevation myocardial infarction even in …

Abstract Primary Percutaneous Coronary Intervention (PCI) has significantly contributed to
reducing the mortality of patients with ST-segment elevation myocardial infarction (STEMI) …

Background—Mineralocorticoid receptor antagonism reduces mortality associated with
heart failure by mechanisms that remain unclear. The effects of the mineralocorticoid …

Background—Intravenous nicorandil, a hybrid compound of ATP-sensitive potassium
channel opener and nitric oxide donor, has been reported to ameliorate early functional and …

Aims Non-invasive assessment of stable chest pain patients is a critical determinant of
resource utilization and clinical outcomes. Increasingly coronary computed tomography …

Objectives The 1-year data from the international ADVANCE (Assessing Diagnostic Value of
Non-invasive FFRCT in Coronary Care) Registry of patients undergoing coronary computed …

Rheumatoid arthritis (RA) is one of the most critical articular diseases with synovial
hyperplasia followed by impairment of quality of life. However, the mechanism (s) that …

Synoviolin, also called HRD1, is an E3 ubiquitin ligase and is implicated in endoplasmic
reticulum‐associated degradation. In mammals, Synoviolin plays crucial roles in various …

Background Adoption of the results of large-scale randomized controlled trials in
percutaneous coronary intervention (PCI) may differ internationally, yet few studies have …