Treatment patterns, persistence and adherence rates in patients with type 2 diabetes mellitus in Japan: a claims-based cohort study

R Nishimura, H Kato, K Kisanuki, A Oh, S Hiroi… - BMJ open, 2019 - bmjopen.bmj.com
Objective To determine real-world trends in antidiabetic drug use, and persistence and
adherence, in Japanese patients with type 2 diabetes mellitus (T2DM). Design …

Efficacy and safety of alogliptin in Japanese patients with type 2 diabetes mellitus: a randomized, double-blind, dose-ranging comparison with placebo, followed by a …

Y Seino, T Fujita, S Hiroi, M Hirayama… - … medical research and …, 2011 - Taylor & Francis
Objective: To compare the efficacy and safety of different dosages of alogliptin with that of
placebo and voglibose in drug-naïve Japanese patients with type 2 diabetes inadequately …

Impact of health insurance coverage for Helicobacter pylori gastritis on the trends in eradication therapy in Japan: retrospective observational study and simulation …

S Hiroi, K Sugano, S Tanaka, K Kawakami - BMJ open, 2017 - bmjopen.bmj.com
Objectives To explore the prevalence of Helicobacter pylori infection in Japan and the trends
of its eradication therapy before and after the changes of the insurance coverage policy, first …

Alogliptin plus voglibose in Japanese patients with type 2 diabetes: a randomized, double-blind, placebo-controlled trial with an open-label, long-term extension

Y Seino, T Fujita, S Hiroi, M Hirayama… - … Medical Research and …, 2011 - Taylor & Francis
Objective: To compare the efficacy and safety of alogliptin and placebo as add-on therapy in
Japanese patients with type 2 diabetes who experienced inadequate glycemic control on …

[HTML][HTML] Treatment patterns in hyperlipidaemia patients based on administrative claim databases in Japan

M Wake, Y Onishi, F Guelfucci, A Oh, S Hiroi… - Atherosclerosis, 2018 - Elsevier
Background and aims Real-world evidence on treatment of hyperlipidaemia (HLD) in Japan
is limited. We aimed to describe treatment patterns, persistence with, and adherence to …

Prevalence of Helicobacter pylori infection in Asia: remembrance of things past?

K Sugano, S Hiroi, Y Yamaoka - Gastroenterology, 2018 - gastrojournal.org
January 2018 Correspondence 257 estimated prevalence from 2000. Meta-analytic
methodology relying on previously published data cannot accurately reflect such rapid …

Lifestyle factors and efficacy of lifestyle interventions in gastroesophageal reflux disease patients with functional dyspepsia: primary care perspectives from the …

K Haruma, Y Kinoshita, S Sakamoto, K Sanada… - Internal …, 2015 - jstage.jst.go.jp
Objective Although gastroesophageal reflux disease (GERD), a very common disorder
worldwide, is considered to be a lifestyle disease, the pathogenic role of lifestyle factors and …

[HTML][HTML] Changes in platelet counts and thrombocytopenia risk in patients with chronic liver disease with different etiologies using real-world Japanese data

M Yoshida, R Tateishi, S Hiroi, M Fujiwara… - Advances in …, 2022 - Springer
Introduction Thrombocytopenia, a common complication of chronic liver disease (CLD),
adversely affects the treatment in patients requiring invasive procedures. Multiple …

[HTML][HTML] Analysis of antihypertensive treatment using real-world Japanese data—the retrospective study of antihypertensives for lowering blood pressure (REAL) study

M Ohishi, T Yoshida, A Oh, S Hiroi, T Takeshima… - Hypertension …, 2019 - nature.com
Hypertension requires strict treatment because it causes diseases that can lead to death.
Although various classes of antihypertensive drugs are available, the actual status of …

[HTML][HTML] Treatment patterns and adherence to antihypertensive combination therapies in Japan using a claims database

T Ishida, A Oh, S Hiroi, Y Shimasaki, N Nishigaki… - Hypertension …, 2019 - nature.com
Fixed-dose combinations (FDCs) for blood pressure control can simplify prescribing,
improve medication adherence, and be cost-effective. In Japan, real-world data about the …