Executive summary Alzheimer's disease (AD) is the leading cause of dementia, and
because the primary risk factor for AD is old age, the prevalence of the disease is increasing …

During the past decade, a conceptual shift occurred in the field of Alzheimer's disease (AD)
considering the disease as a continuum. Thanks to evolving biomarker research and …

Background Prevention strategies are urgently needed to tackle the growing burden of
Alzheimer's disease. We aimed to assess efficacy of long-term use of standardised ginkgo …

Sarcopenia, the age-associated loss of skeletal muscle mass and function, has considerable
societal consequences for the development of frailty, disability, and health care planning. A …

Background No large trials have been done to investigate the efficacy of an intervention
combining a specific compound and several lifestyle interventions compared with placebo …

OBJECTIVES: To investigate the effectiveness of an exercise program in improving ability to
perform activities of daily living (ADLs), physical performance, and nutritional status and …

Background Definitions and diagnostic criteria for all medical conditions are regularly
subjected to reviews and revisions as knowledge advances. In the field of Alzheimer's …

Background Evidence on preventing Alzheimer's disease (AD) is challenging to interpret
due to varying study designs with heterogeneous endpoints and credibility. We completed a …

Background. A number of clinical conditions have been shown to be associated with frailty in
elderly people. We hypothesized that incapacities on the Instrumental Activities of Daily …

Reducing the risk of dementia can halt the worldwide increase of affected people. The
multifactorial and heterogeneous nature of late‐onset dementia, including Alzheimer's …