User profiles for "author:Samuel Akech"
Samuel AkechKEMRI-Wellcome Trust Research Programme Verified email at kemri-wellcome.org Cited by 10634 |
[HTML][HTML] Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis
Background Antimicrobial resistance (AMR) poses a major threat to human health around
the world. Previous publications have estimated the effect of AMR on incidence, deaths …
the world. Previous publications have estimated the effect of AMR on incidence, deaths …
[HTML][HTML] Criteria for pediatric sepsis—a systematic review and meta-analysis by the pediatric sepsis definition taskforce
Objective: To determine the associations of demographic, clinical, laboratory, organ
dysfunction, and illness severity variable values with: 1) sepsis, severe sepsis, or septic …
dysfunction, and illness severity variable values with: 1) sepsis, severe sepsis, or septic …
[HTML][HTML] Mortality after fluid bolus in African children with severe infection
K Maitland, S Kiguli, RO Opoka, C Engoru… - … England Journal of …, 2011 - Mass Medical Soc
Background The role of fluid resuscitation in the treatment of children with shock and life-
threatening infections who live in resource-limited settings is not established. Methods We …
threatening infections who live in resource-limited settings is not established. Methods We …
[HTML][HTML] Pediatric sepsis definition—a systematic review protocol by the Pediatric Sepsis Definition Taskforce
Objectives: Sepsis is responsible for a substantial proportion of global childhood morbidity
and mortality. However, evidence demonstrates major inaccuracies in the use of the term …
and mortality. However, evidence demonstrates major inaccuracies in the use of the term …
Choice of fluids for resuscitation in children with severe infection and shock: systematic review
S Akech, H Ledermann, K Maitland - Bmj, 2010 - bmj.com
Objective To systemically review the evidence from clinical trials comparing the use of
crystalloids and colloids for fluid resuscitation in children with severe infection. Data sources …
crystalloids and colloids for fluid resuscitation in children with severe infection. Data sources …
[HTML][HTML] Exploring mechanisms of excess mortality with early fluid resuscitation: insightsfrom the FEAST trial
K Maitland, EC George, JA Evans, S Kiguli… - BMC medicine, 2013 - Springer
Background Early rapid fluid resuscitation (boluses) in African children with severe
febrileillnesses increases the 48-hour mortality by 3.3% compared with controls (nobolus) …
febrileillnesses increases the 48-hour mortality by 3.3% compared with controls (nobolus) …
A bibliometric analysis of COVID-19 research in Africa
Background The COVID-19 pandemic has led to an unprecedented global research effort to
build a body of knowledge that can inform mitigation strategies. We carried out a bibliometric …
build a body of knowledge that can inform mitigation strategies. We carried out a bibliometric …
[HTML][HTML] Anaemia and blood transfusion in African children presenting to hospital with severe febrile illness
Background Severe anaemia in children is a leading cause of hospital admission and a
major cause of mortality in sub-Saharan Africa, yet there are limited published data on blood …
major cause of mortality in sub-Saharan Africa, yet there are limited published data on blood …
[HTML][HTML] Volume expansion with albumin compared to gelofusine in children with severe malaria: results of a controlled trial
Objectives Previous studies have shown that in children with severe malaria, resuscitation
with albumin infusion results in a lower mortality than resuscitation with saline infusion …
with albumin infusion results in a lower mortality than resuscitation with saline infusion …
Tackling health professionals' strikes: an essential part of health system strengthening in Kenya
InTroduCTIon Since devolution of healthcare services in 2013, the Kenyan public health
sector has been affected by frequent short and often localised strikes. 1 These were followed …
sector has been affected by frequent short and often localised strikes. 1 These were followed …