Background Modelling studies have been widely used to inform human papillomavirus
(HPV) vaccination policy decisions; however, many models exist and it is not known whether …

Praziquantel is currently the drug of choice for the treatment of schistosomiasis. Selective
treatment of Schistosoma mansoni infections in various endemic countries usually present …

Background Neglected tropical diseases (NTDs) are generally assumed to be concentrated
in poor populations, but evidence on this remains scattered. We describe within-country …

Health policy making in developing countries requires estimates of the (global) burden of
disease. At present, most of the available data on schistosomiasis is limited to numbers of …

Background New WHO guidelines recommend initiation of antiretroviral therapy for HIV-
positive adults with CD4 counts of 500 cells per μL or less, a higher threshold than was …

The aim of this study was to describe spatial and temporal variations in malaria epidemic
risk in Ethiopia and to examine factors involved in relation to their implications for early …

Background This Phase 1/2a study evaluated the safety, immunogenicity, and efficacy of an
experimental malaria vaccine comprised of the recombinant Plasmodium falciparum protein …

The effectiveness of syndromic treatment as an STD control strategy depends on the
proportion of episodes which become symptomatic; few studies have measured this directly …

Background Man to mosquito transmission of malaria depends on the presence of the
sexual stage parasites, gametocytes, that often circulate at low densities. Gametocyte …

Background Since late 2003, highly pathogenic avian influenza (HPAI) outbreaks caused by
infection with H5N1 virus has led to the deaths of millions of poultry and more than 10 …