Frailty and chronic kidney disease: a systematic review

R Chowdhury, NM Peel, M Krosch… - Archives of gerontology …, 2017 - Elsevier
Objective Frailty is associated with increased vulnerability to poor health. There is growing
interest in understanding the association between frailty and chronic kidney disease (CKD) …

Medication prescribing in frail older people

RE Hubbard, MS O'Mahony… - European journal of clinical …, 2013 - Springer
Purpose While some people remain fit and active as they grow older, others experience
complex problems: disease, dependency and disability. Frailty is a term used to describe …

Frailty in older women

RE Hubbard, K Rockwood - Maturitas, 2011 - Elsevier
It is a truth universally acknowledged that although men tend to have better health in old
age, women live longer lives. Here, we briefly review the biological, social and behavioural …

Frailty, body mass index, and abdominal obesity in older people

RE Hubbard, IA Lang, DJ Llewellyn… - … of Gerontology Series …, 2010 - academic.oup.com
Background Frailty has been conceptualized as a wasting disorder with weight loss as a key
component. However, obesity is associated with disability and with physiological markers …

Inflammation and frailty measures in older people

RE Hubbard, MS O'Mahony, GM Savva… - Journal of cellular …, 2009 - Wiley Online Library
Inflammation in patients defined as frail by Fried's phenotypic definition may be related to
sarcopenia. This study aimed to investigate inflammation in older patients across different …

The impact of frailty and delirium on mortality in older inpatients

EMP Eeles, SV White, SM O'Mahony, AJ Bayer… - Age and …, 2012 - academic.oup.com
Background: delirium and frailty are common among hospitalised older people but delirium
is often missed and frailty considered difficult to measure in clinical practice. Objective: to …

Frailty status at admission to hospital predicts multiple adverse outcomes

RE Hubbard, NM Peel, M Samanta, LC Gray… - Age and …, 2017 - academic.oup.com
Aims frailty is proposed as a summative measure of health status and marker of individual
vulnerability. We aimed to investigate the discriminative capacity of a frailty index (FI) …

Predicting outcome after hip fracture: using a frailty index to integrate comprehensive geriatric assessment results

M Krishnan, S Beck, W Havelock, E Eeles… - Age and …, 2014 - academic.oup.com
Introduction: hip fracture is expensive in terms of mortality, hospital length of stay (LOS) and
consequences for independence. Poor outcome reflects the vulnerability of patients who …

Frailty, inflammation and the elderly

RE Hubbard, KW Woodhouse - Biogerontology, 2010 - Springer
Frailty is a term used as a marker of vulnerability, identifying individuals with a diminished
capacity to respond to external stressors. Those who are frail are at increased risk of death …

Neighborhood deprivation, individual socioeconomic status, and frailty in older adults

IA Lang, RE Hubbard, MK Andrew… - Journal of the …, 2009 - Wiley Online Library
OBJECTIVES: To assess how individual socioeconomic status and neighborhood
deprivation affect frailty. DESIGN: Nationally representative population‐based study, the …