Pancreatic cancer

J Kleeff, M Korc, M Apte, C La Vecchia… - Nature reviews Disease …, 2016 - nature.com
Pancreatic cancer is a major cause of cancer-associated mortality, with a dismal overall
prognosis that has remained virtually unchanged for many decades. Currently, prevention or …

[HTML][HTML] Vitamin D supplementation to prevent acute respiratory infections: a systematic review and meta-analysis of aggregate data from randomised controlled trials

DA Jolliffe, CA Camargo, JD Sluyter… - The lancet Diabetes & …, 2021 - thelancet.com
Background A 2017 meta-analysis of data from 25 randomised controlled trials (RCTs) of
vitamin D supplementation for the prevention of acute respiratory infections (ARIs) revealed …

Ozone depletion, ultraviolet radiation, climate change and prospects for a sustainable future

PW Barnes, CE Williamson, RM Lucas… - Nature …, 2019 - nature.com
Abstract Changes in stratospheric ozone and climate over the past 40-plus years have
altered the solar ultraviolet (UV) radiation conditions at the Earth's surface. Ozone depletion …

Global burden of 5 major types of gastrointestinal cancer

M Arnold, CC Abnet, RE Neale, J Vignat… - Gastroenterology, 2020 - Elsevier
Background & Aims There were an estimated 4.8 million new cases of gastrointestinal (GI)
cancers and 3.4 million related deaths, worldwide, in 2018. GI cancers account for 26% of …

Association between telomere length and risk of cancer and non-neoplastic diseases: a Mendelian randomization study

PC Haycock, S Burgess, A Nounu, J Zheng… - JAMA …, 2017 - jamanetwork.com
Importance The causal direction and magnitude of the association between telomere length
and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility …

Common variation at 2p13. 3, 3q29, 7p13 and 17q25. 1 associated with susceptibility to pancreatic cancer

EJ Childs, E Mocci, D Campa, PM Bracci, S Gallinger… - Nature …, 2015 - nature.com
Pancreatic cancer is the fourth leading cause of cancer death in the developed world. Both
inherited high-penetrance mutations in BRCA2 (ref.), ATM, PALB2 (ref.), BRCA1 (ref.) …

Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility

MT Landi, DT Bishop, S MacGregor, MJ Machiela… - Nature …, 2020 - nature.com
Most genetic susceptibility to cutaneous melanoma remains to be discovered. Meta-analysis
genome-wide association study (GWAS) of 36,760 cases of melanoma (67% newly …

The D-Health Trial: a randomised controlled trial of the effect of vitamin D on mortality

RE Neale, C Baxter, BD Romero… - The Lancet Diabetes & …, 2022 - thelancet.com
Background The effect of supplementing unscreened adults with vitamin D 3 on mortality is
unclear. We aimed to determine whether monthly doses of vitamin D 3 influenced mortality …

[HTML][HTML] Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer

AP Klein, BM Wolpin, HA Risch… - Nature …, 2018 - nature.com
Abstract In 2020, 146,063 deaths due to pancreatic cancer are estimated to occur in Europe
and the United States combined. To identify common susceptibility alleles, we performed the …

Environmental effects of ozone depletion, UV radiation and interactions with climate change: UNEP Environmental Effects Assessment Panel, update 2017

AF Bais, RM Lucas, JF Bornman… - Photochemical & …, 2018 - pubs.rsc.org
The Environmental Effects Assessment Panel (EEAP) is one of three Panels of experts that
inform the Parties to the Montreal Protocol. The EEAP focuses on the effects of UV radiation …