ISPAD clinical practice consensus guidelines 2022: Stages of type 1 diabetes in children and
adolescents Page 1 ISPAD GUIDELINES ISPAD clinical practice consensus guidelines 2022 …

Most screening programs to identify individuals at risk for type 1 diabetes have targeted
relatives of people living with the disease to improve yield and feasibility. However,∼ 90 …

Type 1 diabetes (T1D) is an autoimmune disease in which the insulin-producing β cells of
the pancreas are destroyed by T lymphocytes. Recent studies have demonstrated that …

Aims/hypothesis Classically, type 1 diabetes is thought to proceed to absolute insulin
deficiency. Recently developed ultrasensitive assays capable of detecting C-peptide under …

Background Whether improved glucose control with hybrid closed-loop therapy can
preserve C-peptide secretion as compared with standard insulin therapy in persons with …

Background Closed-loop insulin delivery systems have the potential to address suboptimal
glucose control in children and adolescents with type 1 diabetes. We compared safety and …

OBJECTIVE Hepatocyte nuclear factor 1-α (HNF1A)/hepatocyte nuclear factor 4-α (HNF4A)
maturity-onset diabetes of the young (MODY) is frequently misdiagnosed as type 1 diabetes …

OBJECTIVE Mixed-meal tolerance test (MMTT) area under the curve C-peptide (AUC CP) is
the gold-standard measure of endogenous insulin secretion in type 1 diabetes but is …

OBJECTIVE Stimulated serum C-peptide (sCP) during a mixed-meal tolerance test (MMTT)
is the gold standard measure of endogenous insulin secretion, but practical issues limit its …

Importance The incidence of diabetes in childhood has increased during the COVID-19
pandemic. Elucidating whether SARS-CoV-2 infection is associated with islet autoimmunity …