User profiles for "author:Olufunmilayo Lesi"

Olufunmilayo Lesi

Professor of Medicine, University of Lagos
Verified email at who.int
Cited by 6885

Global prevalence and genotype distribution of hepatitis C virus infection in 2015: a modelling study

S Blach, S Zeuzem, M Manns, I Altraif… - The lancet …, 2017 - thelancet.com
Summary Background The 69th World Health Assembly approved the Global Health Sector
Strategy to eliminate hepatitis C virus (HCV) infection by 2030, which can become a reality …

Accelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission

GS Cooke, I Andrieux-Meyer, TL Applegate… - The lancet …, 2019 - thelancet.com
Viral hepatitis is a major public health threat and a leading cause of death worldwide.
Annual mortality from viral hepatitis is similar to that of other major infectious diseases such …

[HTML][HTML] Hepatitis B in sub-Saharan Africa: strategies to achieve the 2030 elimination targets

CW Spearman, M Afihene, R Ally, B Apica… - The lancet …, 2017 - thelancet.com
The WHO global health sector strategy on viral hepatitis, created in May, 2016, aims to
achieve a 90% reduction in new cases of chronic hepatitis B and C and a 65% reduction in …

[HTML][HTML] Global burden of primary liver cancer in 2020 and predictions to 2040

H Rumgay, M Arnold, J Ferlay, O Lesi, CJ Cabasag… - Journal of …, 2022 - Elsevier
Background & Aims The burden of liver cancer varies across the world. Herein, we present
updated estimates of the current global burden of liver cancer (incidence and mortality) and …

[PDF][PDF] The Gambia Liver Cancer Study: Infection with hepatitis B and C and the risk of hepatocellular carcinoma in West Africa

GD Kirk, OA Lesi, M Mendy, AO Akano, O Sam… - …, 2004 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the most common cancer in The Gambia. Hepatitis B
virus (HBV) infection is endemic, with 15% to 20% of the population being chronic carriers …

[HTML][HTML] Characteristics, management, and outcomes of patients with hepatocellular carcinoma in Africa: a multicountry observational study from the Africa Liver …

JD Yang, EA Mohamed, AOA Aziz… - The lancet …, 2017 - thelancet.com
Background Hepatocellular carcinoma is a leading cause of cancer-related death in Africa,
but there is still no comprehensive description of the current status of its epidemiology in …

[HTML][HTML] Worldwide prevalence of hepatitis B virus and hepatitis C virus among patients with cirrhosis at country, region, and global levels: a systematic review

CJ Alberts, GM Clifford, D Georges, F Negro… - The Lancet …, 2022 - thelancet.com
Background Empirical, updated country-level estimates on the proportion of cirrhosis
attributable to viral hepatitis are required. We estimated the prevalence of hepatitis B virus …

249ser TP53 mutation in plasma DNA, hepatitis B viral infection, and risk of hepatocellular carcinoma

GD Kirk, OA Lesi, M Mendy, K Szymañska, H Whittle… - Oncogene, 2005 - nature.com
Hepatocellular carcinoma (HCC) from regions with high dietary exposure to aflatoxins and
endemic for hepatitis B virus (HBV) often contain a specific mutation at codon 249 in TP53 …

[HTML][HTML] Hepatitis C in sub-Saharan Africa: the current status and recommendations for achieving elimination by 2030

MW Sonderup, M Afihene, R Ally, B Apica… - The Lancet …, 2017 - thelancet.com
In 2016, WHO adopted a strategy for the elimination of viral hepatitis by 2030. Africa, and
more specifically, sub-Saharan Africa, carries a substantial portion of the global burden of …

Aflatoxin exposure and viral hepatitis in the etiology of liver cirrhosis in the Gambia, West Africa

MH Kuniholm, OA Lesi, M Mendy… - Environmental …, 2008 - ehp.niehs.nih.gov
Background Cirrhosis of the liver is thought to be a major cause of morbidity and mortality in
sub-Saharan Africa, but few controlled studies on the etiology of cirrhosis have been …