Mechanisms for the bone anabolic effect of parathyroid hormone treatment in humans
D Aslan, MD Andersen, LB Gede… - … journal of clinical and …, 2012 - Taylor & Francis
Intermittent low-dose treatment with parathyroid hormone (PTH) analogues has become
widely used in the treatment of severe osteoporosis. During normal physiological conditions …
widely used in the treatment of severe osteoporosis. During normal physiological conditions …
Osteoporosis in chronic obstructive pulmonary disease patients
NR Jørgensen, P Schwarz - Current Opinion in Pulmonary …, 2008 - journals.lww.com
Patients with chronic obstructive pulmonary disease are at increased risk of osteoporosis
and fractures. Risk factors such as smoking, advanced age, physical inactivity, malnutrition …
and fractures. Risk factors such as smoking, advanced age, physical inactivity, malnutrition …
Effect of whole-body vibration exercise in preventing falls and fractures: a systematic review and meta-analysis
DB Jepsen, K Thomsen, S Hansen, NR Jørgensen… - BMJ open, 2017 - bmjopen.bmj.com
Objective To investigate the effect of whole-body vibration exercise (WBV) on fracture risk in
adults≥ 50 years of age. Design A systematic review and meta-analysis calculating relative …
adults≥ 50 years of age. Design A systematic review and meta-analysis calculating relative …
[HTML][HTML] Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum
MKW Crusell, TH Hansen, T Nielsen, KH Allin… - Microbiome, 2018 - Springer
Background Imbalances of gut microbiota composition are linked to a range of metabolic
perturbations. In the present study, we examined the gut microbiota of women with …
perturbations. In the present study, we examined the gut microbiota of women with …
Dexamethasone, BMP-2, and 1, 25-dihydroxyvitamin D enhance a more differentiated osteoblast phenotype: validation of an in vitro model for human bone marrow …
NR Jørgensen, Z Henriksen, OH Sørensen, R Civitelli - Steroids, 2004 - Elsevier
In vitro models of bone cells are important for the study of bone biology, including the
regulation of bone formation and resorption. In this study, we have validated an in vitro …
regulation of bone formation and resorption. In this study, we have validated an in vitro …
Bone geometry, volumetric density, microarchitecture, and estimated bone strength assessed by HR‐pQCT in adult patients with type 1 diabetes mellitus
The primary goal of this cross‐sectional in vivo study was to assess peripheral bone
microarchitecture, bone strength, and bone remodeling in adult type 1 diabetes (T1D) …
microarchitecture, bone strength, and bone remodeling in adult type 1 diabetes (T1D) …
Compromised cortical bone compartment in type 2 diabetes mellitus patients with microvascular disease
Objective and design Patients with type 2 diabetes mellitus (T2D) have an increased fracture
risk despite a normal or elevated bone mineral density (BMD). The aim of this cross …
risk despite a normal or elevated bone mineral density (BMD). The aim of this cross …
Amylin analog pramlintide induces migraine‐like attacks in patients
Objective Migraine is a prevalent and disabling neurological disease. Its genesis is poorly
understood, and there remains unmet clinical need. We aimed to identify mechanisms and …
understood, and there remains unmet clinical need. We aimed to identify mechanisms and …
[HTML][HTML] Exenatide once weekly for alcohol use disorder investigated in a randomized, placebo-controlled clinical trial
MK Klausen, ME Jensen, M Møller, N Le Dous… - JCI insight, 2022 - ncbi.nlm.nih.gov
Background Alcohol use disorder (AUD) is a chronic, relapsing brain disorder that accounts
for 5% of deaths annually, and there is an urgent need to develop new targets for …
for 5% of deaths annually, and there is an urgent need to develop new targets for …
[HTML][HTML] Effects of dapagliflozin on volume status when added to renin–angiotensin system inhibitors
MK Eickhoff, CCJ Dekkers, BJ Kramers… - Journal of clinical …, 2019 - mdpi.com
Sodium glucose co-transporter 2 (SGLT2) inhibitors reduce the risk of heart and kidney
failure in patients with type 2 diabetes, possibly due to diuretic effects. Previous non-placebo …
failure in patients with type 2 diabetes, possibly due to diuretic effects. Previous non-placebo …