Importance High-dose immunosuppressive therapy and autologous hematopoietic stem cell
transplantation (HSCT) have shown efficacy in systemic sclerosis in phase 1 and small …

Systemic Sclerosis (SSc) is a complex autoimmune disease, characterized by high mortality
and morbidity. The heterogeneity in terms of extent, severity, and rate of progression of skin …

Abstract Coronavirus disease-19 (COVID-19), caused by Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2), represents one of the biggest challenges of 21st …

The term interstitial pneumonia with autoimmune features (IPAF) has been proposed to
define patients with interstitial lung disease (ILD) associated with autoimmune signs not …

It is still uncertain which, if any, immunologic parameters may help diagnose a renal flare of
lupus nephritis. Anti-C1q antibody (Ab) titers have been elevated in patients with lupus with …

Objective. To develop valid instruments for the assessment of disease-related damage and
disease activity in Sjögren's syndrome (SS). Methods. Data on 206 patients with primary SS …

Objective Fibroblasts play a major role in the development of systemic sclerosis (SSc), and
the occurrence of serum autoantibodies reacting with fibroblast plasma membrane antigens …

Abstract Objective Circulating endothelial cells (CECs) have been described in different
conditions involving vascular injury. Vascular abnormalities play a key role in the …

Methods. Thirty-seven untreated white women with primary SS were evaluated clinically and
serologically. Carotid and femoral artery intima-media thickness (IMT) was evaluated in the …

Antisynthetase syndrome (ASSD) is a rare clinical condition that is characterized by the
occurrence of a classic clinical triad, encompassing myositis, arthritis, and interstitial lung …