[HTML][HTML] Monkeypox encephalitis with transverse myelitis in a female patient
J Cole, S Choudry, S Kular, T Payne, S Akili… - The Lancet Infectious …, 2023 - thelancet.com
The 2022 monkeypox outbreak has affected 110 countries worldwide, outside of classic
endemic areas (ie, west Africa and central Africa). On July 23, 2022, the outbreak was …
endemic areas (ie, west Africa and central Africa). On July 23, 2022, the outbreak was …
[HTML][HTML] Rapid antibiotic-resistance predictions from genome sequence data for Staphylococcus aureus and Mycobacterium tuberculosis
The rise of antibiotic-resistant bacteria has led to an urgent need for rapid detection of drug
resistance in clinical samples, and improvements in global surveillance. Here we show how …
resistance in clinical samples, and improvements in global surveillance. Here we show how …
[HTML][HTML] The usefulness of whole genome sequencing in the management of Staphylococcus aureus infections
J Price, NC Gordon, D Crook, M Llewelyn… - Clinical Microbiology and …, 2013 - Elsevier
Staphylococcus aureus remains a leading cause of hospital-acquired and community-
associated infection worldwide. The burden of disease is exacerbated by the emergence of …
associated infection worldwide. The burden of disease is exacerbated by the emergence of …
[HTML][HTML] Adjunctive rifampicin for Staphylococcus aureus bacteraemia (ARREST): a multicentre, randomised, double-blind, placebo-controlled trial
GE Thwaites, M Scarborough, A Szubert, E Nsutebu… - The Lancet, 2018 - thelancet.com
Background Staphylococcus aureus bacteraemia is a common cause of severe community-
acquired and hospital-acquired infection worldwide. We tested the hypothesis that …
acquired and hospital-acquired infection worldwide. We tested the hypothesis that …
Identifying lineage effects when controlling for population structure improves power in bacterial association studies
SG Earle, CH Wu, J Charlesworth, N Stoesser… - Nature …, 2016 - nature.com
Bacteria pose unique challenges for genome-wide association studies because of strong
structuring into distinct strains and substantial linkage disequilibrium across the genome 1 …
structuring into distinct strains and substantial linkage disequilibrium across the genome 1 …
A pilot study of rapid benchtop sequencing of Staphylococcus aureus and Clostridium difficile for outbreak detection and surveillance
Objectives To investigate the prospects of newly available benchtop sequencers to provide
rapid whole-genome data in routine clinical practice. Next-generation sequencing has the …
rapid whole-genome data in routine clinical practice. Next-generation sequencing has the …
[HTML][HTML] AMR Surveillance in low and middle-income settings-A roadmap for participation in the Global Antimicrobial Surveillance System (GLASS)
AC Seale, NC Gordon, J Islam, SJ Peacock… - Wellcome open …, 2017 - ncbi.nlm.nih.gov
Drug-resistant infections caused by bacteria with increasing antimicrobial resistance (AMR)
threaten our ability to treat life-threatening conditions. Tackling AMR requires international …
threaten our ability to treat life-threatening conditions. Tackling AMR requires international …
Severe infections emerge from commensal bacteria by adaptive evolution
Bacteria responsible for the greatest global mortality colonize the human microbiota far more
frequently than they cause severe infections. Whether mutation and selection among …
frequently than they cause severe infections. Whether mutation and selection among …
Accuracy of different bioinformatics methods in detecting antibiotic resistance and virulence factors from Staphylococcus aureus whole-genome sequences
In principle, whole-genome sequencing (WGS) can predict phenotypic resistance directly
from a genotype, replacing laboratory-based tests. However, the contribution of different …
from a genotype, replacing laboratory-based tests. However, the contribution of different …
Survival following Staphylococcus aureus bloodstream infection: a prospective multinational cohort study assessing the impact of place of care
Background Staphylococcus aureus bloodstream infection (SAB) is a common, life-
threatening infection with a high mortality. Survival can be improved by implementing quality …
threatening infection with a high mortality. Survival can be improved by implementing quality …