Oral vaccines are less immunogenic when given to infants in low-income compared with
high-income countries, limiting their potential public health impact. Here, we review factors …

Rotaviruses are generally species-specific, but cross-species transmission is possible, as
has been demonstrated experimentally. Several case studies have indicated infection of …

There is extensive antigenic and genomic diversity among co‐circulating human rotaviruses.
They are differentiated into groups, subgroups and types. There are at least 7 groups (A–G) …

In April 2008, a nucleotide-sequence-based, complete genome classification system was
developed for group A rotaviruses (RVs). This system assigns a specific genotype to each of …

Group A rotavirus classification is currently based on the molecular properties of the two
outer layer proteins, VP7 and VP4, and the middle layer protein, VP6. As reassortment of all …

Recently, a classification system was proposed for rotaviruses in which all the 11 genomic
RNA segments are used (Matthijnssens et al. in J Virol 82: 3204–3219, 2008). Based on …

The use of molecular methods for rotavirus characterisation provides not only increased
sensitivity for typing, but also allows accurate and more complete characterisation of strains …

ABSTRACT A reverse transcription-PCR (RT-PCR) was established to amplify a 379-bp
cDNA fragment (nucleotides 747 to 1126, coding for amino acids 241 to 367) of the VP6 …

ABSTRACT G12 rotaviruses were first detected in diarrheic children in the Philippines in
1987, but no further cases were reported until 1998. However, G12 rotaviruses have been …

The G and P genotypes of 3,601 rotavirus strains collected in the United Kingdom between
1995 and 1999 were determined (M. Iturriza-Gómara et al., J. Clin. Microbiol. 38: 4394 …