User profiles for "author:Michael Y Tsai"
 | Michael Y TsaiProfessor of laboratory medicine and pathology, University of Minnesota Verified email at umn.edu Cited by 32872 |
Cystathionine β‐synthase mutations in homocystinuria
JP Kraus, M Janošík, V Kožich, R Mandell… - Human …, 1999 - Wiley Online Library
The major cause of homocystinuria is mutation of the gene encoding the enzyme
cystathionine β‐synthase (CBS). Deficiency of CBS activity results in elevated levels of …
cystathionine β‐synthase (CBS). Deficiency of CBS activity results in elevated levels of …
[PDF][PDF] Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data
Objective To use the rs1229984 variant in the alcohol dehydrogenase 1B gene (ADH1B) as
an instrument to investigate the causal role of alcohol in cardiovascular disease. Design …
an instrument to investigate the causal role of alcohol in cardiovascular disease. Design …
Mendelian randomization of blood lipids for coronary heart disease
Aims To investigate the causal role of high-density lipoprotein cholesterol (HDL-C) and
triglycerides in coronary heart disease (CHD) using multiple instrumental variables for …
triglycerides in coronary heart disease (CHD) using multiple instrumental variables for …
Prospective study of coronary heart disease incidence in relation to fasting total homocysteine, related genetic polymorphisms, and B vitamins: the Atherosclerosis …
AR Folsom, FJ Nieto, PG McGovern, MY Tsai… - Circulation, 1998 - Am Heart Assoc
Background—Elevated plasma total homocysteine (tHcy), low B-vitamin intake, and genetic
polymorphisms related to tHcy metabolism may play roles in coronary heart disease (CHD) …
polymorphisms related to tHcy metabolism may play roles in coronary heart disease (CHD) …
LDL particle subclasses, LDL particle size, and carotid atherosclerosis in the Multi-Ethnic Study of Atherosclerosis (MESA)
S Mora, M Szklo, JD Otvos, P Greenland, BM Psaty… - Atherosclerosis, 2007 - Elsevier
BACKGROUND: Previous studies showing that smaller low-density lipoprotein (LDL) size is
associated with greater atherosclerotic risk did not adequately control for small and large …
associated with greater atherosclerotic risk did not adequately control for small and large …
Incorporation and clearance of omega-3 fatty acids in erythrocyte membranes and plasma phospholipids
J Cao, KA Schwichtenberg, NQ Hanson… - Clinical …, 2006 - academic.oup.com
Background: The sum of eicosapentaenoic acid (EPA, 20: 5 ω3) and docosahexaenoic acid
(DHA, 22: 6 ω3) in erythrocyte membranes, termed the omega-3 index, can indicate …
(DHA, 22: 6 ω3) in erythrocyte membranes, termed the omega-3 index, can indicate …
[PDF][PDF] Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks
Low-frequency coding DNA sequence variants in the proprotein convertase subtilisin/kexin
type 9 gene (PCSK9) lower plasma low-density lipoprotein cholesterol (LDL-C), protect …
type 9 gene (PCSK9) lower plasma low-density lipoprotein cholesterol (LDL-C), protect …
[HTML][HTML] Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium
RN Lemaitre, T Tanaka, W Tang, A Manichaikul… - PLoS …, 2011 - journals.plos.org
Long-chain n-3 polyunsaturated fatty acids (PUFAs) can derive from diet or from α-linolenic
acid (ALA) by elongation and desaturation. We investigated the association of common …
acid (ALA) by elongation and desaturation. We investigated the association of common …
ω-3 polyunsaturated fatty acid biomarkers and coronary heart disease: pooling project of 19 cohort studies
Importance The role of ω-3 polyunsaturated fatty acids for primary prevention of coronary
heart disease (CHD) remains controversial. Most prior longitudinal studies evaluated self …
heart disease (CHD) remains controversial. Most prior longitudinal studies evaluated self …
[HTML][HTML] Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study
T Tanaka, J Shen, GR Abecasis, A Kisialiou… - PLoS …, 2009 - journals.plos.org
Polyunsaturated fatty acids (PUFA) have a role in many physiological processes, including
energy production, modulation of inflammation, and maintenance of cell membrane integrity …
energy production, modulation of inflammation, and maintenance of cell membrane integrity …