Objectives Overutilisation of antibiotics may contribute to the emergence of antimicrobial
drug resistance, a growing international concern. This study aimed to analyse the …

Objectives To identify and quantify inappropriate systemic antibiotic prescribing in primary
care in England, and ultimately to determine the potential for reduction in prescribing of …

Background: Of children with acute otitis media (AOM), 15%–20% present with acute onset
ear discharge due to a spontaneous perforation of the tympanic membrane (AOMd). This …

Objective To determine whether the incidence of pneumonia, peritonsillar abscess,
mastoiditis, empyema, meningitis, intracranial abscess, and Lemierre's syndrome is higher …

Objectives To evaluate the effectiveness and safety at population scale of electronically
delivered prescribing feedback and decision support interventions at reducing antibiotic …

Background The obesity epidemic has major public health consequences. Expert dietetic
and behavioural counselling with intensive follow-up is effective, but resource requirements …

Background There is a need for cost-effective weight management interventions that primary
care can deliver to reduce the morbidity caused by obesity. Automated web-based …

Objective The aims of this study were to test whether yeast-derived β-1, 3/1, 6 glucan can
prevent the occurrence or reduce the severity of upper respiratory tract infection (URTI) and …

PURPOSE This study aimed to implement a point-of-care cluster randomized trial using
electronic health records. We evaluated the effectiveness of electronically delivered decision …

Background: Behavioural counselling with intensive follow-up for obesity is effective, but in
resource-constrained primary care settings briefer approaches are needed. Objectives: To …