Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia
Q Zhou, ME Munger, RG Veenstra… - Blood, The Journal …, 2011 - ashpublications.org
Tumor-associated immune suppression can lead to defective T cell-mediated antitumor
immunity. Here, we identified a unique phenotype of exhausted T cells in mice with …
immunity. Here, we identified a unique phenotype of exhausted T cells in mice with …
Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid …
Tumor-induced immune defects can weaken host immune response and permit tumor cell
growth. In a systemic model of murine acute myeloid leukemia (AML), tumor progression …
growth. In a systemic model of murine acute myeloid leukemia (AML), tumor progression …
Depletion of endogenous tumor-associated regulatory T cells improves the efficacy of adoptive cytotoxic T-cell immunotherapy in murine acute myeloid leukemia
Tumor-induced immune suppression can permit tumor cells to escape host immune
resistance. To elucidate host factors contributing to the poor response of adoptively …
resistance. To elucidate host factors contributing to the poor response of adoptively …
Long‐term outcomes after selective dorsal rhizotomy: a retrospective matched cohort study
ME Munger, N Aldahondo, LE Krach… - … Medicine & Child …, 2017 - Wiley Online Library
Aim To examine long‐term outcomes of selective dorsal rhizotomy (SDR) 10 to 17 years
after surgery. Method Participants who underwent SDR had spastic diplegic cerebral palsy …
after surgery. Method Participants who underwent SDR had spastic diplegic cerebral palsy …
Long-term outcomes of distal femoral extension osteotomy and patellar tendon advancement in individuals with cerebral palsy
Background: We examined long-term outcomes across the domains of the International
Classification of Functioning, Disability and Health for 2 groups of participants with cerebral …
Classification of Functioning, Disability and Health for 2 groups of participants with cerebral …
Repeatability of electromyography recordings and muscle synergies during gait among children with cerebral palsy
Background Clinical gait analysis is commonly used in the evaluation and treatment of
children with cerebral palsy (CP). While the repeatability of kinematic and kinetic measures …
children with cerebral palsy (CP). While the repeatability of kinematic and kinetic measures …
Selective dorsal rhizotomy in ambulant children with cerebral palsy
Background Selective dorsal rhizotomy (SDR) is a surgical procedure for treating spasticity
in ambulant children with cerebral palsy (CP). However, controversies remain regarding …
in ambulant children with cerebral palsy (CP). However, controversies remain regarding …
Long‐term effects of spasticity treatment, including selective dorsal rhizotomy, for individuals with cerebral palsy
BA MacWilliams, ML McMulkin, EA Duffy… - … Medicine & Child …, 2022 - Wiley Online Library
Aim To understand the long‐term effects of comprehensive spasticity treatment, including
selective dorsal rhizotomy (SDR), on individuals with spastic cerebral palsy. Method This …
selective dorsal rhizotomy (SDR), on individuals with spastic cerebral palsy. Method This …
Comparing the effects of two spasticity management strategies on the long-term outcomes of individuals with bilateral spastic cerebral palsy: a multicentre cohort study …
Introduction Spasticity is one of the primary pathologies associated with cerebral palsy (CP),
yet no definitive evidence exists to guide the appropriate level of spasticity management for …
yet no definitive evidence exists to guide the appropriate level of spasticity management for …
Factor analysis of the Gait Outcomes Assessment List's goal questions: A new method to measure goal prioritization in ambulatory individuals with cerebral palsy
Aim To evaluate the factor structure of the 49 goal prioritization questions of the Gait
Outcome Assessment List (GOAL). Method This was a retrospective review of 622 …
Outcome Assessment List (GOAL). Method This was a retrospective review of 622 …