Objective To determine whether clinicians' prognoses in patients with severe acute
exacerbations of obstructive lung disease admitted to intensive care match observed …

Introduction Recurrent pulmonary exacerbations lead to progressive lung damage in cystic
fibrosis (CF). Inhaled medications (mucoactive agents and antibiotics) help prevent …

Introduction: Decisions about the intensity of treatment for patients with acute exacerbations
of chronic obstructive pulmonary disease (AECOPD) are influenced by predictions about …

BACKGROUND: Decisions about how to treat patients with acute exacerbations of
obstructive airways disease—chronic obstructive pulmonary disease (COPD), asthma or …

CFHealthHub is a learning health system active in over 50% of adult CF Centres in England,
supporting people with CF to develop habits of self-care around adherence to preventative …

Among adults with cystic fibrosis (CF), medication adherence is low and reasons for low
adherence are poorly understood. Our previous exploratory study showed that stronger …

Background Preventative medication reduces hospitalisations in people with cystic fibrosis
(PWCF) but adherence is poor. We assessed the feasibility of a randomised controlled trial …

Cystic fibrosis [CF] is a chronic disease in which preventative treatment with nebulised
antibiotics can reduce pulmonary exacerbations that otherwise require rescue therapy …

Background People with cystic fibrosis frequently have low levels of adherence to inhaled
medications. Objectives The objectives were to develop and evaluate an intervention for …

Methods This retrospective multicenter observational study included adult CF centers in
Sheffield (n= 95), Southampton (n= 101), and Nottingham (n= 103), which are first-wave …