Abstract Apolipoprotein E ε4 (APOE* 4) is the only fully established susceptibility allele for
Alzheimer's disease. One of the most studied candidates is the insertion (I)/deletion (D) …

The traditional approach in case-control association studies, to evaluate candidate genes
individually, either single markers or haplotypes, has had limited success. The multifactorial …

Context Permanent childhood hearing loss (PCHL) can affect speech, language, and wider
outcomes. Adverse effects are mitigated through universal newborn hearing screening …

Aim: In the United Kingdom (UK) and Ireland, avoidance of breastfeeding and alternative
combinations of antiretroviral therapy regimen and mode of delivery are recommended …

Objectives: To analyze mother-to-child HIV transmission (MTCT) rates over time in light of
changes in management, demographic, and pregnancy characteristics. Design: Population …

Muscle function often becomes progressively more compromised in children with spastic
cerebral palsy, leading to reduced mobility. This study aimed to examine the role that muscle …

Background When using accelerometers to measure physical activity, researchers need to
determine whether subjects have worn their device for a sufficient period to be included in …

Sandhoff disease is a neurodegenerative disorder resulting from the autosomal recessive
inheritance of mutations in the HEXB gene, which encodes the β-subunit of β …

Objective To describe levels of physical activity, sedentary time and adherence to Chief
Medical Officers (CMO) physical activity guidelines among primary school-aged children …

Postnatal depression and anxiety have been shown to increase the risk of disturbances in
mother–child interaction and child development. Research into mechanisms has focused on …