Autologous hematopoietic stem cell transplantation vs intravenous pulse cyclophosphamide in diffuse cutaneous systemic sclerosis: a randomized clinical trial

JM Van Laar, D Farge, JK Sont, K Naraghi… - Jama, 2014 - jamanetwork.com
Importance High-dose immunosuppressive therapy and autologous hematopoietic stem cell
transplantation (HSCT) have shown efficacy in systemic sclerosis in phase 1 and small …

High prevalence of BRAF V600E mutations in Erdheim-Chester disease but not in other non-Langerhans cell histiocytoses

J Haroche, F Charlotte, L Arnaud… - Blood, The Journal …, 2012 - ashpublications.org
Histiocytoses are rare disorders of unknown origin with highly heterogeneous prognosis.
BRAF mutations have been observed in Langerhans cell histiocytosis (LCH). We …

[HTML][HTML] Toward a better understanding of the atypical features of chronic graft-versus-host disease: a report from the 2020 National Institutes of Health Consensus …

GDE Cuvelier, M Schoettler, NP Buxbaum… - … and cellular therapy, 2022 - Elsevier
Alloreactive and autoimmune responses after allogeneic hematopoietic cell transplantation
can occur in nonclassical chronic graft-versus-host disease (chronic GVHD) tissues and …

Imatinib compared with chemotherapy as front‐line treatment of elderly patients with Philadelphia chromosome‐positive acute lymphoblastic leukemia (Ph+ ALL)

OG Ottmann, B Wassmann, H Pfeifer… - … Journal of the …, 2007 - Wiley Online Library
BACKGROUND Elderly patients with Philadelphia chromosome‐positive acute
lymphoblastic leukemia (Ph+ ALL) have a poor prognosis, with a low complete remission …

Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations

J Thalhammer, G Kindle, A Nieters, S Rusch… - Journal of Allergy and …, 2021 - Elsevier
Background Inborn errors of immunity (IEI) are rare diseases, which makes diagnosis a
challenge. A better description of the initial presenting manifestations should improve …

[PDF][PDF] Gp130 and ras mediated signaling in human plasma cell line INA-6: a cytokine-regulated tumor model for plasmacytoma

R Burger, A Guenther, F Bakker… - The Hematology …, 2001 - researchgate.net
Plasmacytoma is a clonal B-cell neoplasm in which malignant plasma cells accumulate in
the bone marrow. Treatment of the disease has been difficult and the fiveyear survival rate …

[HTML][HTML] The German national registry of primary immunodeficiencies (2012–2017)

SM El-Helou, AK Biegner, S Bode, SR Ehl… - Frontiers in …, 2019 - frontiersin.org
Introduction: The German PID-NET registry was founded in 2009, serving as the first national
registry of patients with primary immunodeficiencies (PID) in Germany. It is part of the …

[HTML][HTML] Disease progression in systemic sclerosis-overlap syndrome is significantly different from limited and diffuse cutaneous systemic sclerosis

P Moinzadeh, E Aberer, K Ahmadi-Simab… - Annals of the …, 2015 - ard.bmj.com
Background Systemic sclerosis (SSc)-overlap syndromes are a very heterogeneous and
remarkable subgroup of SSc-patients, who present at least two connective tissue diseases …

[HTML][HTML] Pro-and anti-inflammatory responses in severe COVID-19-induced acute respiratory distress syndrome—an observational pilot study

Q Notz, M Schmalzing, F Wedekink… - Frontiers in …, 2020 - frontiersin.org
Objectives The severity of Coronavirus Disease 2019 (COVID-19) is largely determined by
the immune response. First studies indicate altered lymphocyte counts and function …

[HTML][HTML] Autologous stem cell transplantation for progressive systemic sclerosis: a prospective non-interventional study from the European Society for Blood and …

J Henes, MC Oliveira, M Labopin, M Badoglio… - …, 2021 - ncbi.nlm.nih.gov
Three randomized controlled trials in early severe systemic sclerosis demonstrated that
autologous hematopoietic stem cell transplantation was superior to standard …