How does exercise treatment compare with antihypertensive medications? A network meta-analysis of 391 randomised controlled trials assessing exercise and …
Objective To compare the effect of exercise regimens and medications on systolic blood
pressure (SBP). Data sources Medline (via PubMed) and the Cochrane Library. Eligibility …
pressure (SBP). Data sources Medline (via PubMed) and the Cochrane Library. Eligibility …
Subclinical hypothyroidism and the risk of stroke events and fatal stroke: an individual participant data analysis
L Chaker, C Baumgartner… - The Journal of …, 2015 - academic.oup.com
Objective: The objective was to determine the risk of stroke associated with subclinical
hypothyroidism. Data Sources and Study Selection: Published prospective cohort studies …
hypothyroidism. Data Sources and Study Selection: Published prospective cohort studies …
Subclinical thyroid dysfunction and the risk for fractures: a systematic review and meta-analysis
CD Wirth, MR Blum, BR da Costa… - Annals of internal …, 2014 - acpjournals.org
Background: Data on the association between subclinical thyroid dysfunction and fractures
conflict. Purpose: To assess the risk for hip and nonspine fractures associated with …
conflict. Purpose: To assess the risk for hip and nonspine fractures associated with …
[HTML][HTML] Thyroid hormone therapy for older adults with subclinical hypothyroidism
Background The use of levothyroxine to treat subclinical hypothyroidism is controversial. We
aimed to determine whether levothyroxine provided clinical benefits in older persons with …
aimed to determine whether levothyroxine provided clinical benefits in older persons with …
Subclinical thyroid dysfunction and fracture risk: a meta-analysis
Importance Associations between subclinical thyroid dysfunction and fractures are unclear
and clinical trials are lacking. Objective To assess the association of subclinical thyroid …
and clinical trials are lacking. Objective To assess the association of subclinical thyroid …
Optimizing therapy to prevent avoidable hospital admissions in multimorbid older adults (OPERAM): cluster randomised controlled trial
MR Blum, BTGM Sallevelt, A Spinewine, D O'Mahony… - bmj, 2021 - bmj.com
Objective To examine the effect of optimising drug treatment on drug related hospital
admissions in older adults with multimorbidity and polypharmacy admitted to hospital …
admissions in older adults with multimorbidity and polypharmacy admitted to hospital …
Association between levothyroxine treatment and thyroid-related symptoms among adults aged 80 years and older with subclinical hypothyroidism
SP Mooijaart, RS Du Puy, DJ Stott, PM Kearney… - Jama, 2019 - jamanetwork.com
Importance It is unclear whether levothyroxine treatment provides clinically important
benefits in adults aged 80 years and older with subclinical hypothyroidism. Objective To …
benefits in adults aged 80 years and older with subclinical hypothyroidism. Objective To …
Thyroid function within the reference range and the risk of stroke: an individual participant data analysis
L Chaker, C Baumgartner… - The Journal of …, 2016 - academic.oup.com
Context: The currently applied reference ranges for thyroid function are under debate.
Despite evidence that thyroid function within the reference range is related with several …
Despite evidence that thyroid function within the reference range is related with several …
Association between subclinical thyroid dysfunction and change in bone mineral density in prospective cohorts
Background Subclinical hyperthyroidism (SH yper) has been associated with increased risk
of hip and other fractures, but the linking mechanisms remain unclear. Objective To …
of hip and other fractures, but the linking mechanisms remain unclear. Objective To …
Limitations and misinterpretations of E-values for sensitivity analyses of observational studies
JPA Ioannidis, YJ Tan, MR Blum - Annals of internal medicine, 2019 - acpjournals.org
The E-value was recently introduced on the basis of earlier work as “the minimum strength of
association… that an unmeasured confounder would need to have with both the treatment …
association… that an unmeasured confounder would need to have with both the treatment …