How does exercise treatment compare with antihypertensive medications? A network meta-analysis of 391 randomised controlled trials assessing exercise and …

H Naci, M Salcher-Konrad, S Dias, MR Blum… - British journal of sports …, 2019 - bjsm.bmj.com
Objective To compare the effect of exercise regimens and medications on systolic blood
pressure (SBP). Data sources Medline (via PubMed) and the Cochrane Library. Eligibility …

Subclinical hypothyroidism and the risk of stroke events and fatal stroke: an individual participant data analysis

L Chaker, C Baumgartner… - The Journal of …, 2015 - academic.oup.com
Objective: The objective was to determine the risk of stroke associated with subclinical
hypothyroidism. Data Sources and Study Selection: Published prospective cohort studies …

Subclinical thyroid dysfunction and the risk for fractures: a systematic review and meta-analysis

CD Wirth, MR Blum, BR da Costa… - Annals of internal …, 2014 - acpjournals.org
Background: Data on the association between subclinical thyroid dysfunction and fractures
conflict. Purpose: To assess the risk for hip and nonspine fractures associated with …

[HTML][HTML] Thyroid hormone therapy for older adults with subclinical hypothyroidism

DJ Stott, N Rodondi, PM Kearney, I Ford… - … England Journal of …, 2017 - Mass Medical Soc
Background The use of levothyroxine to treat subclinical hypothyroidism is controversial. We
aimed to determine whether levothyroxine provided clinical benefits in older persons with …

Subclinical thyroid dysfunction and fracture risk: a meta-analysis

MR Blum, DC Bauer, TH Collet, HA Fink, AR Cappola… - Jama, 2015 - jamanetwork.com
Importance Associations between subclinical thyroid dysfunction and fractures are unclear
and clinical trials are lacking. Objective To assess the association of subclinical thyroid …

Optimizing therapy to prevent avoidable hospital admissions in multimorbid older adults (OPERAM): cluster randomised controlled trial

MR Blum, BTGM Sallevelt, A Spinewine, D O'Mahony… - bmj, 2021 - bmj.com
Objective To examine the effect of optimising drug treatment on drug related hospital
admissions in older adults with multimorbidity and polypharmacy admitted to hospital …

Association between levothyroxine treatment and thyroid-related symptoms among adults aged 80 years and older with subclinical hypothyroidism

SP Mooijaart, RS Du Puy, DJ Stott, PM Kearney… - Jama, 2019 - jamanetwork.com
Importance It is unclear whether levothyroxine treatment provides clinically important
benefits in adults aged 80 years and older with subclinical hypothyroidism. Objective To …

Thyroid function within the reference range and the risk of stroke: an individual participant data analysis

L Chaker, C Baumgartner… - The Journal of …, 2016 - academic.oup.com
Context: The currently applied reference ranges for thyroid function are under debate.
Despite evidence that thyroid function within the reference range is related with several …

Association between subclinical thyroid dysfunction and change in bone mineral density in prospective cohorts

D Segna, DC Bauer, M Feller… - Journal of internal …, 2018 - Wiley Online Library
Background Subclinical hyperthyroidism (SH yper) has been associated with increased risk
of hip and other fractures, but the linking mechanisms remain unclear. Objective To …

Limitations and misinterpretations of E-values for sensitivity analyses of observational studies

JPA Ioannidis, YJ Tan, MR Blum - Annals of internal medicine, 2019 - acpjournals.org
The E-value was recently introduced on the basis of earlier work as “the minimum strength of
association… that an unmeasured confounder would need to have with both the treatment …