Pregnancy is an immune paradox in which the mother must tolerate the fetus, a
semiallograft, while at the same time maintain immune defense against pathogens. From the …

BACKGROUND The endometrium is a highly dynamic tissue that undergoes dramatic
proliferation and differentiation monthly in order to prepare the uterus for implantation and …

Extracellular vesicles (EV s) extruded by the human placenta are increasingly being
recognized as an essential mode of feto‐maternal communication. In the past two decades …

STUDY QUESTION What proteins are carried by extracellular vesicles (EVs) released from
normal first trimester placentae? SUMMARY ANSWER One thousand five hundred and …

Ovarian cancer is the third most common gynaecological malignancy. Changes in circadian
rhythms such as bright light exposure may affect female reproductive physiology. Night shift …

In preeclampsia, the serum levels of transthyretin, a carrier protein for thyroxine, are
elevated. Transthyretin isolated from preeclamptic serum is also aggregated and can induce …

STUDY QUESTION How do nano-vesicles extruded from normal first trimester human
placentae affect maternal vascular function? SUMMARY ANSWER Placental nano-vesicles …

Background/objectives Preeclampsia is a life-threatening hypertensive disease affecting 3–
5% of pregnancies. While the pathogenesis of preeclampsia remains unclear, it is known …

Background Irregular menstrual cycles including the length of cycles and menses, and
heavy menstrual blood loss are linked to many gynaecological diseases. Obesity has been …

Preterm birth is a major contributor to neonatal mortality and morbidity, and infection is a
major risk factor. Chorioamnionitis, inflammation of the placenta, and fetal membranes (FMs) …