The fly Drosophila melanogaster is one of the most intensively studied organisms in biology
and serves as a model system for the investigation of many developmental and cellular …

We herein present an overview of the upcoming 5th edition of the World Health Organization
Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms. Myeloid …

The human genome is thought to harbor 50,000 to 100,000 genes, of which about half have
been sampled to date in the form of expressed sequence tags. An international consortium …

Background In a phase 1–2 trial of albumin-bound paclitaxel (nab-paclitaxel) plus
gemcitabine, substantial clinical activity was noted in patients with advanced pancreatic …

Genomic sequencing has made it clear that a large fraction of the genes specifying the core
biological functions are shared by all eukaryotes. Knowledge of the biological role of such …

OBJECTIVE To evaluate the prevalence and time trends for diagnosed and undiagnosed
diabetes, impaired fasting glucose, and impaired glucose tolerance in US adults by age …

Many tumour cells have elevated rates of glucose uptake but reduced rates of oxidative
phosphorylation. This persistence of high lactate production by tumours in the presence of …

beta-Amyloid is a 39-to 43-amino-acid neurotoxic peptide that aggregates to form the core of
Alzheimer disease-associated senile (amyloid) plaques. No satisfactory hypothesis has yet …

Background The role of adjuvant chemotherapy in stage II colon cancer continues to be
debated. The presence of circulating tumor DNA (ctDNA) after surgery predicts very poor …

Summary Background Pandemic H1N1 2009 influenza virus has been identified as the
cause of a widespread outbreak of febrile respiratory infection in the USA and worldwide …