Strengthening the Reporting of Observational Studies in Epidemiology for Newborn Infection (STROBE-NI): an extension of the STROBE statement for neonatal …
EJA Fitchett, AC Seale, S Vergnano… - The Lancet infectious …, 2016 - thelancet.com
Neonatal infections are estimated to account for a quarter of the 2· 8 million annual neonatal
deaths, as well as approximately 3% of all disability-adjusted life-years. Despite this burden …
deaths, as well as approximately 3% of all disability-adjusted life-years. Despite this burden …
[HTML][HTML] Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial
AM Dondorp, CI Fanello, ICE Hendriksen, E Gomes… - The Lancet, 2010 - thelancet.com
Background Severe malaria is a major cause of childhood death and often the main reason
for paediatric hospital admission in sub-Saharan Africa. Quinine is still the established …
for paediatric hospital admission in sub-Saharan Africa. Quinine is still the established …
Efficacy of RTS, S/AS02 malaria vaccine against Plasmodium falciparum infection in semi-immune adult men in The Gambia: a randomised trial
KA Bojang, PJM Milligan, M Pinder, L Vigneron… - The Lancet, 2001 - thelancet.com
Summary Background RTS, S/AS02 is a pre-erythrocytic malaria vaccine based on the
circumsporozoite surface protein of Plasmodium falciparum fused to HBsAg, incorporating a …
circumsporozoite surface protein of Plasmodium falciparum fused to HBsAg, incorporating a …
[HTML][HTML] The African genome variation project shapes medical genetics in Africa
Given the importance of Africa to studies of human origins and disease susceptibility,
detailed characterization of African genetic diversity is needed. The African Genome …
detailed characterization of African genetic diversity is needed. The African Genome …
[HTML][HTML] Changes in malaria indices between 1999 and 2007 in The Gambia: a retrospective analysis
SJ Ceesay, C Casals-Pascual, J Erskine, SE Anya… - The Lancet, 2008 - thelancet.com
Background Malaria is a major cause of morbidity and mortality in Africa. International effort
and funding for control has been stepped up, with substantial increases from 2003 in the …
and funding for control has been stepped up, with substantial increases from 2003 in the …
[HTML][HTML] Genome-wide and fine-resolution association analysis of malaria in West Africa
We report a genome-wide association (GWA) study of severe malaria in The Gambia. The
initial GWA scan included 2,500 children genotyped on the Affymetrix 500K GeneChip, and …
initial GWA scan included 2,500 children genotyped on the Affymetrix 500K GeneChip, and …
Informed consent comprehension in A frican research settings
MO Afolabi, JU Okebe, N McGrath… - Tropical medicine & …, 2014 - Wiley Online Library
Objective Previous reviews on participants' comprehension of informed consent information
have focused on developed countries. Experience has shown that ethical standards …
have focused on developed countries. Experience has shown that ethical standards …
[HTML][HTML] Malaria in infants aged less than six months-is it an area of unmet medical need?
U D'Alessandro, D Ubben, K Hamed, SJ Ceesay… - Malaria journal, 2012 - Springer
Despite the protection provided by several factors, including maternal antibodies, the burden
of malaria in young infants may be higher than previously thought. Infants with congenital or …
of malaria in young infants may be higher than previously thought. Infants with congenital or …
[HTML][HTML] A novel chimpanzee adenovirus vector with low human seroprevalence: improved systems for vector derivation and comparative immunogenicity
Recombinant adenoviruses are among the most promising tools for vaccine antigen
delivery. Recently, the development of new vectors has focused on serotypes to which the …
delivery. Recently, the development of new vectors has focused on serotypes to which the …
Absence of Putative Artemisinin Resistance Mutations Among Plasmodium falciparum in Sub-Saharan Africa: A Molecular Epidemiologic Study
Plasmodium falciparum parasites that are resistant to artemisinins have been detected in
Southeast Asia. Resistance is associated with several polymorphisms in the parasite's K13 …
Southeast Asia. Resistance is associated with several polymorphisms in the parasite's K13 …