Experimental approaches directed at addressing these issues are limited by several
considerations. First, the close association between obesity and OSA often obscures …

Obstructive sleep apnoea (OSA) is a common disorder in which repetitive apnoeas expose
the cardiovascular system to cycles of hypoxia, exaggerated negative intrathoracic pressure …

causing the rib cage and abdomen to distort and move out of phase. In contrast, in central
events respiratory movements are absent or attenuated, but in phase. The reported …

In previous analyses of the occurrence of central (CSA) and obstructive sleep apnea (OSA)
in patients with congestive heart failure (CHF), only men were studied and risk factors for …

Background Obstructive sleep apnea subjects the failing heart to adverse hemodynamic and
adrenergic loads and may thereby contribute to the progression of heart failure. We …

Background The Canadian Continuous Positive Airway Pressure for Patients with Central
Sleep Apnea and Heart Failure trial tested the hypothesis that continuous positive airway …

Objectives: This study sought to determine, in patients with heart failure (HF), whether
untreated moderate to severe obstructive sleep apnea (OSA) is associated with a higher …

Background—In the main analysis of the Canadian Continuous Positive Airway Pressure
(CPAP) for Patients with Central Sleep Apnea (CSA) and Heart Failure Trial (CANPAP) …

There are few epidemiological studies in which the prevalence of CSA in patients with HF
has been examined. The 2 largest studies involving 450 and 81 patients reported …

Disturbances in cardiovascular neural regulation, influencing both disease course and
survival, progress as heart failure worsens. Heart failure due to left ventricular systolic …