User profiles for "author:Jean Regina"

Jean Regina

- Verified email at chuv.ch - Cited by 1139

Jean Marques Regina

- Verified email at vradvogados.adv.br - Cited by 41

[HTML][HTML] The cytokines HGF and CXCL13 predict the severity and the mortality in COVID-19 patients

M Perreau, M Suffiotti, P Marques-Vidal… - Nature …, 2021 - nature.com
The objective of the present study was to identify biological signatures of severe coronavirus
disease 2019 (COVID-19) predictive of admission in the intensive care unit (ICU). Over 170 …

[HTML][HTML] Epidemiology, risk factors and clinical course of SARS-CoV-2 infected patients in a Swiss university hospital: an observational retrospective study

J Regina, M Papadimitriou-Olivgeris, R Burger… - PLoS …, 2020 - journals.plos.org
Background This study aims to describe the epidemiology of COVID-19 patients in a Swiss
university hospital. Methods This retrospective observational study included all adult …

[HTML][HTML] Post‑COVID‑19 syndrome in outpatients: a cohort study

F Desgranges, E Tadini, A Munting, J Regina… - Journal of General …, 2022 - Springer
Background After mild COVID-19, some outpatients experience persistent symptoms.
However, data are scarce and prospective studies are urgently needed. Objectives To …

[HTML][HTML] Predicting venous thromboembolic events in patients with coronavirus disease 2019 requiring hospitalization: an observational retrospective study by the …

E Kampouri, P Filippidis, B Viala, M Méan… - BioMed research …, 2020 - hindawi.com
Background. Coronavirus disease 2019 (COVID-19) can result in profound changes in
blood coagulation. The aim of the study was to determine the incidence and predictors of …

[HTML][HTML] COVID‐19 rapidly increases MDSCs and prolongs innate immune dysfunctions

IT Schrijver, C Théroude, N Antonakos… - European Journal of …, 2022 - ncbi.nlm.nih.gov
We used unsupervised immunophenotyping of blood leukocytes and measured cytokine
production by innate immune cell exposed to LPS and R848. We show that COVID‐19 …

[HTML][HTML] Sepsis awareness and knowledge amongst nurses, physicians and paramedics of a tertiary care center in Switzerland: A survey-based cross-sectional study

J Regina, MA Le Pogam, T Niemi, R Akrour, S Pepe… - PloS one, 2023 - journals.plos.org
Background Sepsis is a leading cause of morbidity and mortality. Prompt recognition and
management are critical to improve outcomes. Methods We conducted a survey among …

SARS-CoV-2 seroprevalence in healthcare workers of a Swiss tertiary care centre at the end of the first wave: a cross-sectional study

S Meylan, U Dafni, F Lamoth, Z Tsourti, MA Lobritz… - BMJ open, 2021 - bmjopen.bmj.com
Objective To assess the SARS-CoV-2 transmission in healthcare workers (HCWs) using
seroprevalence as a surrogate marker of infection in our tertiary care centre according to …

[HTML][HTML] Dual deletion of the sirtuins SIRT2 and SIRT3 impacts on metabolism and inflammatory responses of macrophages and protects from endotoxemia

T Heinonen, E Ciarlo, E Rigoni, J Regina… - Frontiers in …, 2019 - frontiersin.org
Sirtuin 2 (SIRT2) and SIRT3 are cytoplasmic and mitochondrial NAD-dependent
deacetylases. SIRT2 and SIRT3 target proteins involved in metabolic, proliferation and …

An Early Warning Score to predict ICU admission in COVID-19 positive patients

S Meylan, R Akrour, J Regina, PA Bart… - Journal of …, 2020 - journalofinfection.com
Coronavirus disease 2019 (COVID-19) bears several challenging problems, including
insidious symptom onset, subclinical manifestations and highly transmissible property …

[HTML][HTML] Impact of 2020 EUCAST criteria on meropenem prescription for the treatment of Pseudomonas aeruginosa infections: an observational study in a university …

A Munting, J Regina, J Damas, L Lhopitallier… - Clinical Microbiology …, 2022 - Elsevier
Objectives We aimed to evaluate the impact of the 10th version of European Committee on
Antimicrobial Susceptibility Testing (EUCAST) breakpoints table, where most …