Introduction: A spectrum of non-motor manifestations in amyotrophic lateral sclerosis (ALS)
patients has been increasingly recognized, with cognitive and behavioral impairments the …

Previously thought to be a pure motor disease, amyotrophic lateral sclerosis (ALS) is now
established as multisystem neurodegenerative disorder that lies on a continuum with …

Objectives: To investigate patient susceptibility to neuropsychiatric symptoms in the context
of progression of more classic motor symptoms in amyotrophic lateral sclerosis (ALS) and to …

Objectives: To determine the frequency and correlates of apathy in amyotrophic lateral
sclerosis (ALS) and its influence on the prognosis of the disease. Methods: Three databases …

Background and purpose Apathy is the most commonly reported behavioural change in
amyotrophic lateral sclerosis (ALS). However, the degree to which it affects prognosis and …

Aims To determine the underlying cellular changes and clinical correlates associated with
pathology of the hypothalamus in amyotrophic lateral sclerosis (ALS), as hypothalamic …

Background: Patients with frontotemporal dementia (FTD) and amyotrophic lateral sclerosis
(ALS) exhibit changes in eating behavior that could potentially affect lipid levels. Objective …

There is need for a valid, sensitive and short instrument capable of detecting and quantifying
behavioural changes in ALS, which can be utilized in clinical and research settings. This …

Objective Physiological changes potentially influence disease progression and survival
along the Amyotrophic Lateral Sclerosis (ALS)‐Frontotemporal dementia (FTD) spectrum …

The disease syndromes of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia
(FTD) display considerable clinical, genetic and pathological overlap, yet mounting …