The COVID-19 pandemic is an unprecedented healthcare emergency causing mortality and
illness across the world. Although primarily affecting the lungs, the SARS-CoV-2 virus also …

Blood vessels are exposed to multiple mechanical forces that are exerted on the vessel wall
(radial, circumferential and longitudinal forces) or on the endothelial surface (shear stress) …

Microvesicles are members of the family of extracellular vesicles shed from the plasma
membrane of activated or apoptotic cells. Microvesicles were initially characterised by their …

Although paracrine effects of mesenchymal stem cells (MSCs) have been suggested
previously, cardioprotection by human MSC secretions has never been demonstrated …

Objectives: This study sought to examine whether exenatide is capable of reducing
myocardial infarct size. Background: Exenatide is a glucagon-like peptide (GLP)-1 analogue …

Recent studies suggest that the therapeutic effects of stem cell transplantation following
myocardial infarction (MI) are mediated by paracrine factors. One of the main goals in the …

Background—Reperfusion therapy for myocardial infarction is hampered by detrimental
inflammatory responses partly via Toll-like receptor (TLR) activation. Targeting TLR …

Left ventricular (LV) remodeling leads to congestive heart failure and is a main determinant
of morbidity and mortality following myocardial infarction. Therapeutic options to prevent LV …

Aims Myocardial infarction (MI) triggers an intense inflammatory response that is associated
with infarct expansion and is detrimental for cardiac function. Interleukin (IL)-1β and IL-18 …

Blood-based liquid biopsies, including tumor-educated blood platelets (TEPs), have
emerged as promising biomarker sources for non-invasive detection of cancer. Here we …