The etiology of Parkinson's disease (PD) is not well understood but likely to involve both
genetic and environmental factors. Incidence and prevalence estimates vary to a large …

Nasopharyngeal carcinoma (NPC) has a unique and complex etiology that is not completely
understood. Although NPC is rare in most populations, it is a leading form of cancer in a few …

Abstract Background Sub-Saharan Africa (SSA) has a disproportionate burden of both
infectious and chronic diseases compared with other world regions. Current disease …

Background. The risk of colorectal cancer is increased among patients with ulcerative colitis.
The magnitude of this increase in risk and the effects of the length of follow-up, the extent of …

Background In 2002, we reported the initial results of a trial comparing radical prostatectomy
with watchful waiting in the management of early prostate cancer. After three more years of …

Background Although colonoscopy is widely used as a screening test to detect colorectal
cancer, its effect on the risks of colorectal cancer and related death is unclear. Methods We …

Importance The 2008 Physical Activity Guidelines for Americans recommended a minimum
of 75 vigorous-intensity or 150 moderate-intensity minutes per week (7.5 metabolic …

Background Radical prostatectomy reduces mortality among men with localized prostate
cancer; however, important questions regarding long-term benefit remain. Methods Between …

Importance Leisure-time physical activity has been associated with lower risk of heart-
disease and all-cause mortality, but its association with risk of cancer is not well understood …

Background In 2008, we reported that radical prostatectomy, as compared with watchful
waiting, reduces the rate of death from prostate cancer. After an additional 3 years of follow …