[HTML][HTML] Prevalence and risk factors for delirium in critically ill patients with COVID-19 (COVID-D): a multicentre cohort study

BT Pun, R Badenes, GH La Calle, OM Orun… - The Lancet …, 2021 - thelancet.com
Background To date, 750 000 patients with COVID-19 worldwide have required mechanical
ventilation and thus are at high risk of acute brain dysfunction (coma and delirium). We …

Comparison of two delayed strategies for renal replacement therapy initiation for severe acute kidney injury (AKIKI 2): a multicentre, open-label, randomised …

S Gaudry, D Hajage, L Martin-Lefevre, S Lebbah… - The Lancet, 2021 - thelancet.com
Background Delaying renal replacement therapy (RRT) for some time in critically ill patients
with severe acute kidney injury and no severe complication is safe and allows optimisation …

Effect of postextubation high-flow nasal oxygen with noninvasive ventilation vs high-flow nasal oxygen alone on reintubation among patients at high risk of extubation …

AW Thille, G Muller, A Gacouin, R Coudroy… - Jama, 2019 - jamanetwork.com
Importance High-flow nasal oxygen may prevent postextubation respiratory failure in the
intensive care unit (ICU). The combination of high-flow nasal oxygen with noninvasive …

Potentially modifiable factors contributing to sepsis-associated encephalopathy

R Sonneville, E de Montmollin, J Poujade… - Intensive care …, 2017 - Springer
Purpose Identifying modifiable factors for sepsis-associated encephalopathy may help
improve patient care and outcomes. Methods We conducted a retrospective analysis of a …

[HTML][HTML] Spontaneous-breathing trials with pressure-support ventilation or a T-piece

AW Thille, A Gacouin, R Coudroy… - … England Journal of …, 2022 - Mass Medical Soc
Background Spontaneous-breathing trials can be performed with the use of either pressure-
support ventilation (PSV) or a T-piece. Whether PSV trials may result in a shorter time to …

Attributable mortality of ICU-acquired bloodstream infections: impact of the source, causative micro-organism, resistance profile and antimicrobial therapy

C Adrie, M Garrouste-Orgeas, WI Essaied… - Journal of infection, 2017 - Elsevier
Objectives ICU-acquired bloodstream infection (ICUsingle bondBSI) in Intensive Care unit
(ICU) is still associated with a high mortality rate. The increase of antimicrobial drug …

[HTML][HTML] Five days of postoperative antimicrobial therapy decreases infectious complications following pancreaticoduodenectomy in patients at risk for bile …

I Sourrouille, S Gaujoux, G Lacave, F Bert, S Dokmak… - HPB, 2013 - Elsevier
Objectives Pancreaticoduodenectomy (PD) is associated with high morbidity, in part as a
result of infectious complications increased by preoperative bile contamination. The aim of …

Beneficial Effects of Noninvasive Ventilation after Extubation in Obese or Overweight Patients: A Post Hoc Analysis of a Randomized Clinical Trial

AW Thille, R Coudroy, MA Nay, A Gacouin… - American Journal of …, 2022 - atsjournals.org
Rationale: Although noninvasive ventilation (NIV) may prevent reintubation in patients at
high risk of extubation failure in ICUs, this oxygenation strategy has not been specifically …

Pressure-support ventilation vs T-piece during spontaneous breathing trials before extubation among patients at high risk of extubation failure: a post-hoc analysis of a …

AW Thille, R Coudroy, MA Nay, A Gacouin, A Demoule… - Chest, 2020 - Elsevier
Background Spontaneous breathing trial (SBT) using a T-piece remains the most frequently
performed trial before extubation in ICUs. Research Question We aimed at determining …

Effect of transfusion on mortality and other adverse events among critically ill septic patients: an observational study using a marginal structural cox model

C Dupuis, M Garrouste-Orgeas, S Bailly… - Critical Care …, 2017 - journals.lww.com
Objectives: RBC transfusion is often required in patients with sepsis. However, adverse
events have been associated with RBC transfusion, raising safety concerns. A randomized …