Magnesium is the second most abundant intracellular cation and the fourth most common
cation in the body [1]. Its importance as an essential nutrient has been recognized since …

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) represent a
spectrum of acute respiratory failure with diffuse, bilateral lung injury and severe hypoxemia …

Objectives The purpose of this study was to determine whether apoptosis is a major
mechanism of cell death in patients with sepsis. The activities of caspase-3 and the …

J t has been 25 years since Rosen et aP first described the disorder of pulmonary alveolar
proteinosis. Since that time, a great deal has been written about this unusual and fascinating …

Objective.—To test the effect of a novel bradykinin antagonist, deltibant (CP-0127), on
survival, organ dysfunction, and other outcomes in patients with the systemic inflammatory …

Severe pain syndromes reduce quality of life in patients with inflammatory and neoplastic
diseases, often because chronic opiate therapy results in reduced analgesic effectiveness …

To understand the processes involved in the development of MSOF, we will first define what
is meant by the terms sepsis, shock, MSOF, malignant intravascular inflammation …

Gram-negative bacterial infection predisposes to the development of shock and acute lung
injury with multiple organ dysfunction in the critically ill. Although overexpression of …

The aim of the present study was to assess the relative contributions of peroxynitrite
formation following induction of nitric-oxide synthase (iNOS) in the pathophysiology of …

Despite increasing sophistication in antimicrobial therapy and intensive care support of
failing organs, mortality in critically ill patients with the adult respiratory distress syndrome …