User profiles for "author:Frank Struyf"

Frank Struyf

GlaxoSmithKline
Verified email at gsk.com
Cited by 16201

[HTML][HTML] Safety and efficacy of single-dose Ad26. COV2. S vaccine against Covid-19

J Sadoff, G Gray, A Vandebosch… - … England Journal of …, 2021 - Mass Medical Soc
Abstract Background The Ad26. COV2. S vaccine is a recombinant, replication-incompetent
human adenovirus type 26 vector encoding full-length severe acute respiratory syndrome …

Efficacy of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by oncogenic HPV types (PATRICIA): final …

J Paavonen, P Naud, J Salmerón, CM Wheeler… - The Lancet, 2009 - thelancet.com
Background The human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine was
immunogenic, generally well tolerated, and effective against HPV-16 or HPV-18 infections …

Efficacy of a prophylactic adjuvanted bivalent L1 virus-like-particle vaccine against infection with human papillomavirus types 16 and 18 in young women: an interim …

J Paavonen, D Jenkins, FX Bosch, P Naud, J Salmerón… - The Lancet, 2007 - thelancet.com
Background The aim of this interim analysis of a large, international phase III study was to
assess the efficacy of an AS04 adjuvanted L1 virus-like-particle prophylactic candidate …

[HTML][HTML] Interim results of a phase 1–2a trial of Ad26. COV2. S Covid-19 vaccine

J Sadoff, M Le Gars, G Shukarev… - … England Journal of …, 2021 - Mass Medical Soc
Background Efficacious vaccines are urgently needed to contain the ongoing coronavirus
disease 2019 (Covid-19) pandemic of infection with severe acute respiratory syndrome …

Overall efficacy of HPV-16/18 AS04-adjuvanted vaccine against grade 3 or greater cervical intraepithelial neoplasia: 4-year end-of-study analysis of the randomised …

M Lehtinen, J Paavonen, CM Wheeler… - The lancet …, 2012 - thelancet.com
Background Cervical intraepithelial neoplasia grade 2 or greater (CIN2+) is the surrogate
endpoint used in licensure trials of human papillomavirus (HPV) vaccines. Vaccine efficacy …

[HTML][HTML] Immunogenicity of Ad26. COV2. S vaccine against SARS-CoV-2 variants in humans

G Alter, J Yu, J Liu, A Chandrashekar, EN Borducchi… - Nature, 2021 - nature.com
Abstract The Ad26. COV2. S vaccine,–has demonstrated clinical efficacy against
symptomatic COVID-19, including against the B. 1.351 variant that is partially resistant to …

[HTML][HTML] Final analysis of efficacy and safety of single-dose Ad26. COV2. S

J Sadoff, G Gray, A Vandebosch… - … England Journal of …, 2022 - Mass Medical Soc
Abstract Background The Ad26. COV2. S vaccine was highly effective against severe–
critical coronavirus disease 2019 (Covid-19), hospitalization, and death in the primary phase …

Immunogenicity of the Ad26. COV2. S Vaccine for COVID-19

KE Stephenson, M Le Gars, J Sadoff, AM de Groot… - Jama, 2021 - jamanetwork.com
Importance Control of the global COVID-19 pandemic will require the development and
deployment of safe and effective vaccines. Objective To evaluate the immunogenicity of the …

[HTML][HTML] Durable humoral and cellular immune responses 8 months after Ad26. COV2. S vaccination

DH Barouch, KE Stephenson, J Sadoff… - … England Journal of …, 2021 - Mass Medical Soc
Durability of Response after Ad26. COV2. S Vaccination In this study, investigators
measured immune responses in 20 participants who had received either one or two doses …

Cross-protective efficacy of HPV-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by non-vaccine oncogenic HPV types: 4-year end-of …

CM Wheeler, X Castellsagué, SM Garland… - The lancet …, 2012 - thelancet.com
Background We evaluated the efficacy of the human papillomavirus HPV-16/18 AS04-
adjuvanted vaccine against non-vaccine oncogenic HPV types in the end-of-study analysis …