Occipital brain injury associated with neonatal hypoglycemia can result in long-term
disability, epilepsy, and visual impairment. The etiology of this pattern of injury is unclear; …

In the post-DCCT (Diabetes Control and Complications Trial)(1) and-EDIC (Epidemiology of
Diabetes Interventions and Complications)(2) eras, considerable effort has been expended …

Diabetes is one of the most common chronic medical disorders in children. The
management of diabetes remains a substantial burden on children with diabetes and their …

Context: AIP mutations (AIPmut) give rise to a pituitary adenoma predisposition that occurs
in familial isolated pituitary adenomas and less often in sporadic cases. The clinical and …

Background Janus kinase (JAK) inhibitors, including baricitinib, block cytokine signaling and
are effective disease-modifying treatments for several autoimmune diseases. Whether …

OBJECTIVE—In this study, we used neurocognitive assessment and neuroimaging to
examine brain function in youth with type 1 diabetes studied prospectively from diagnosis …

OBJECTIVE To investigate the impact of new-onset diabetic ketoacidosis (DKA) during
childhood on brain morphology and function. RESEARCH DESIGN AND METHODS …

Importance Hybrid closed-loop (HCL) therapy has improved glycemic control in children and
adolescents with type 1 diabetes; however, the efficacy of HCL on glycemic and …

Background KCNJ11 mutations cause permanent neonatal diabetes through pancreatic
ATP-sensitive potassium channel activation. 90% of patients successfully transfer from …

In humans, activation of genes in the testis-determining pathway at 7–8 weeks gestation
causes the bipotential gonad to develop as a testis. The first morphologically recognisable …