Obesity and a central body fat distribution, hypertension, insulin resistance, glucose
intolerance, dyslipidemia, and proinflammatory and prothrombotic factors are all part of the …

Obesity is associated with insulin resistance, hypertension and cardiovascular disease, but
the mechanisms underlying these associations are incompletely understood. Microvascular …

Background—Obesity is associated with an increased risk of developing microangiopathy,
hypertension, and insulin resistance. We hypothesized that obesity is a primary cause of …

Aims The global epidemic of diabetes mellitus continues to expand, including its large
impact on national health care. Measuring diabetes outcomes and their causes of variation …

Background Patients with type 1 diabetes who have impaired awareness of hypoglycaemia
have a three to six times increased risk of severe hypoglycaemia. We aimed to assess …

Capillary rarefaction occurs in many tissues in patients with essential hypertension and may
contribute to an increased vascular resistance and impaired muscle metabolism …

Current strategies combining anti-angiogenic drugs with chemotherapy provide clinical
benefit in cancer patients. It is assumed that anti-angiogenic drugs, such as bevacizumab …

Background—A strong but presently unexplained inverse association between blood
pressure and insulin sensitivity has been reported. Microvascular vasodilator capacity may …

To test the hypothesis that free fatty acids (FFAs) modulate microvascular function and that
this contributes to obesity-associated insulin resistance, hypertension, and microangiopathy …

Microvascular recruitment in muscle is a determinant of insulin sensitivity. Whether
perivascular adipose tissue (PVAT) is involved in disturbed insulin-induced vasoreactivity is …