Persistent ill health after acute COVID-19—referred to as long COVID, the post-acute COVID-
19 syndrome, or the post-COVID-19 condition—has emerged as a major concern. We …

Background The development of tumor necrosis factor α (TNF-α) antagonists has made it
feasible to investigate the role of this cytokine in refractory asthma. Methods We measured …

Over the last decade, technological advances have revolutionised efforts to understand the
role played by microbes in airways disease. With the application of ever more sophisticated …

Background: Non-eosinophilic asthma is a potentially important clinicopathological
phenotype since there is evidence that it responds poorly to inhaled corticosteroid therapy …

U-BIOPRED is a European Union consortium of 20 academic institutions, 11 pharmaceutical
companies and six patient organisations with the objective of improving the understanding …

Rationale: Current asthma guidelines recommend adjusting antiinflammatory treatment on
the basis of the results of lung function tests and symptom assessment, neither of which are …

Background There is debate about the mechanisms of persistent airflow limitation in patients
with asthma. Chronic inflammation is assumed to be important, although there is limited and …

U-BIOPRED aims to characterise paediatric and adult severe asthma using conventional
and innovative systems biology approaches. A total of 99 school-age children with severe …

Summary Background The Single combination budesonide–formoterol inhaler Maintenance
And Reliever Therapy (SMART) regimen reduces severe asthma exacerbations in patients …

Background Few genetic studies that focus on moderate-to-severe asthma exist. We aimed
to identity novel genetic variants associated with moderate-to-severe asthma, see whether …