Background falls and fall-related injuries are common in older adults, have negative effects
on functional independence and quality of life and are associated with increased morbidity …

Clinicians and researchers have shown increasing interest in frailty. Yet, there is still
considerable uncertainty regarding the concept and its definition. In this article, we present …

This chapter examines the current state of research on frailty. A number of competing and
complementary models for its development are described, followed by a working definition …

Background: There is no single generally accepted clinical definition of frailty. Previously
developed tools to assess frailty that have been shown to be predictive of death or need for …

Between 1977 and 1984, 48 girls but only 26 boys were born to parents exposed to 2, 3, 7, 8
tetrachlorodibenzo-p-dioxin (TCDD, or dioxin) in Seveso, Italy. 1 The 1976 industrial …

Background. Frailty and fitness are important attributes of older persons, but population
samples of their prevalence, attributes, and outcomes are limited. Methods. The authors …

Background Recent reports suggest a possibly protective effect for statins in patients with
Alzheimer disease. This association could be due to indication bias, ie, people who elect to …

OBJECTIVE To provide a comprehensive review of the literature on the measurement,
correlates, and health outcomes of medication adherence among community-dwelling older …

Importance Depression is common in individuals with mild cognitive impairment (MCI) and
may confer a higher likelihood of progression to dementia. Prevalence estimates of …

Study Objective: To describe a population that was categorized as" cognitively impaired not
demented"(CIND) and to examine the utility of some of the proposed criteria for describing …