Intensive insulin therapy and mortality among critically ill patients: a meta-analysis including NICE-SUGAR study data

DEG Griesdale, RJ de Souza, RM van Dam… - Cmaj, 2009 - Can Med Assoc
Background: Hyperglycemia is associated with increased mortality in critically ill patients.
Randomized trials of intensive insulin therapy have reported inconsistent effects on mortality …

Should immunonutrition become routine in critically ill patients?: A systematic review of the evidence

DK Heyland, F Novak, JW Drover, M Jain, X Su… - Jama, 2001 - jamanetwork.com
ContextSeveral nutrients have been shown to influence immunologic and inflammatory
responses in humans. Whether these effects translate into an improvement in clinical …

Does enteral nutrition compared to parenteral nutrition result in better outcomes in critically ill adult patients? A systematic review of the literature

L Gramlich, K Kichian, J Pinilla, NJ Rodych, R Dhaliwal… - Nutrition, 2004 - Elsevier
OBJECTIVE: Nutritional support is part of the standard of care for the critically ill adult
patient. In the average patient in the intensive care unit who has no contraindications to …

Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients

DK Heyland, R Dhaliwal, JW Drover… - Journal of Parenteral …, 2003 - Wiley Online Library
OBJECTIVE: This study was conducted to develop evidence‐based clinical practice
guidelines for nutrition support (ie, enteral and parenteral nutrition) in mechanically …

[HTML][HTML] The relationship between nutritional intake and clinical outcomes in critically ill patients: results of an international multicenter observational study

C Alberda, L Gramlich, N Jones, K Jeejeebhoy… - Intensive care …, 2009 - Springer
Purpose The objective of this study was to examine the relationship between the amount of
energy and protein administered and clinical outcomes, and the extent to which pre-morbid …

[HTML][HTML] Defining advance care planning for adults: a consensus definition from a multidisciplinary Delphi panel

RL Sudore, HD Lum, JJ You, LC Hanson… - Journal of pain and …, 2017 - Elsevier
Context Despite increasing interest in advance care planning (ACP) and previous ACP
descriptions, a consensus definition does not yet exist to guide clinical, research, and policy …

The attributable morbidity and mortality of ventilator-associated pneumonia in the critically ill patient

DK Heyland, DJ Cook, L Griffith, SP Keenan… - American journal of …, 1999 - atsjournals.org
To evaluate the attributable morbidity and mortality of ventilator-associated pneumonia
(VAP) in intensive care unit (ICU) patients, we conducted a prospective, matched cohort …

Stress ulcer prophylaxis in critically III patients: resolving discordant meta-analyses

DJ Cook, BK Reeve, GH Guyatt, DK Heyland… - Jama, 1996 - jamanetwork.com
Purpose.—To resolve discrepancies in previous systematic overviews and provide
estimates of the effect of stress ulcer prophylaxis on gastrointestinal bleeding, pneumonia …

Definition and recommendations for advance care planning: an international consensus supported by the European Association for Palliative Care

JAC Rietjens, RL Sudore, M Connolly… - The Lancet …, 2017 - thelancet.com
Advance care planning (ACP) is increasingly implemented in oncology and beyond, but a
definition of ACP and recommendations concerning its use are lacking. We used a formal …

Glutamine supplementation in serious illness: a systematic review of the evidence

F Novak, DK Heyland, A Avenell, JW Drover… - Critical care …, 2002 - journals.lww.com
Glutamine supplementation in serious illness: A systematic r... : Critical Care Medicine
Glutamine supplementation in serious illness: A systematic review of the evidence* : Critical …