SGLT2 inhibitors and GLP-1 receptor agonists: established and emerging indications
E Brown, HJL Heerspink, DJ Cuthbertson, JPH Wilding - The Lancet, 2021 - thelancet.com
SGLT2 inhibitors and GLP-1 receptor agonists are used in patients with type 2 diabetes as
glucose lowering therapies, with additional benefits of weight loss and blood pressure …
glucose lowering therapies, with additional benefits of weight loss and blood pressure …
Diabetic peripheral neuropathy: epidemiology, diagnosis, and pharmacotherapy
Z Iqbal, S Azmi, R Yadav, M Ferdousi, M Kumar… - Clinical …, 2018 - Elsevier
Purpose Diabetic peripheral neuropathy (DPN) is the commonest cause of neuropathy
worldwide, and its prevalence increases with the duration of diabetes. It affects …
worldwide, and its prevalence increases with the duration of diabetes. It affects …
Reduced physical activity in young and older adults: metabolic and musculoskeletal implications
KA Bowden Davies, S Pickles… - Therapeutic …, 2019 - journals.sagepub.com
Background: Although the health benefits of regular physical activity and exercise are well
established and have been incorporated into national public health recommendations, there …
established and have been incorporated into national public health recommendations, there …
Multiorgan impairment in low-risk individuals with post-COVID-19 syndrome: a prospective, community-based study
Objective To assess medium-term organ impairment in symptomatic individuals following
recovery from acute SARS-CoV-2 infection. Design Baseline findings from a prospective …
recovery from acute SARS-CoV-2 infection. Design Baseline findings from a prospective …
[HTML][HTML] Improved glycaemia correlates with liver fat reduction in obese, type 2 diabetes, patients given glucagon-like peptide-1 (GLP-1) receptor agonists
DJ Cuthbertson, A Irwin, CJ Gardner, C Daousi… - PloS one, 2012 - journals.plos.org
Glucagon-like peptide-1 receptor agonists (GLP-1 RA) are effective for obese patients with
type 2 diabetes mellitus (T2DM) because they concomitantly target obesity and …
type 2 diabetes mellitus (T2DM) because they concomitantly target obesity and …
Polycystic ovary syndrome with hyperandrogenism is characterized by an increased risk of hepatic steatosis compared to nonhyperandrogenic PCOS phenotypes and …
Context: Nonalcoholic fatty liver disease may be evident in women with polycystic ovary
syndrome (PCOS), both conditions being associated with obesity and insulin resistance …
syndrome (PCOS), both conditions being associated with obesity and insulin resistance …
Effectiveness of metyrapone in treating Cushing's syndrome: a retrospective multicenter study in 195 patients
Background: Cushing's syndrome (CS) is a severe condition with excess mortality and
significant morbidity necessitating control of hypercortisolemia. There are few data …
significant morbidity necessitating control of hypercortisolemia. There are few data …
Diagnosing and managing carcinoid heart disease in patients with neuroendocrine tumors: an expert statement
J Davar, HM Connolly, ME Caplin, M Pavel… - Journal of the American …, 2017 - jacc.org
Carcinoid heart disease is a frequent occurrence in patients with carcinoid syndrome and is
responsible for substantial morbidity and mortality. The pathophysiology of carcinoid heart …
responsible for substantial morbidity and mortality. The pathophysiology of carcinoid heart …
Anabolic signaling and protein synthesis in human skeletal muscle after dynamic shortening or lengthening exercise
DJ Cuthbertson, J Babraj, K Smith… - American Journal …, 2006 - journals.physiology.org
We hypothesized a differential activation of the anabolic signaling proteins protein kinase B
(PKB) and p70 S6 kinase (p70S6K) and subsequent differential stimulation of human …
(PKB) and p70 S6 kinase (p70S6K) and subsequent differential stimulation of human …
Weight loss variability with SGLT2 inhibitors and GLP‐1 receptor agonists in type 2 diabetes mellitus and obesity: mechanistic possibilities
E Brown, JPH Wilding, TM Barber, U Alam… - Obesity …, 2019 - Wiley Online Library
We are facing a global epidemic of obesity and type 2 diabetes. Weight loss, in the context of
obesity and type 2 diabetes, may improve glycaemic control and weight‐related …
obesity and type 2 diabetes, may improve glycaemic control and weight‐related …