The double-stranded RNA-dependent protein kinase PKR is a critical mediator of the
antiproliferative and antiviral effects exerted by interferons. Not only is PKR an effector …

Objective Smartphone games that aim to alter health behaviours are common, but there is
uncertainty about how to achieve this. We systematically reviewed health apps containing …

Drugs encapsulation is a suitable strategy in order to cope with the limitations of
conventional dosage forms such as unsuitable bioavailability, stability, taste, and odor …

Importance A comprehensive understanding of the benefits of COVID-19 vaccination
requires consideration of disease attenuation, determined as whether people who develop …

Objectives To characterize the clinical severity of covid-19 associated with the alpha, delta,
and omicron SARS-CoV-2 variants among adults admitted to hospital and to compare the …

Purpose: To investigate the proportion of breast cancers arising in patients with germ line
BRCA1 and BRCA2 mutations expressing basal markers and developing predictive tests for …

The Spanish PETHEMA group designed a protocol for newly diagnosed PML/RAR-
positive acute promyelocytic leukemia (APL) in which induction and consolidation followed …

ALTHOUGH vitamin C is critical to human physiology1–5, it is not clear how it is taken up
into cells. The kinetics of cell and tissue accumulation of ascorbic acid in vitro indicate that …

Phenolic acids (benzoic, phenylacetic and phenylpropionic acids) are the most abundant
phenolic structures found in fecal water. As an approach towards the exploration of their …

This Campbell systematic review assesses the effects of advocacy interventions on intimate
partner violence and women's wellbeing. The review summarizes findings from 13 studies …