[HTML][HTML] Diagonal earlobe crease (Frank's Sign) for diagnosis of coronary artery disease: a systematic review of diagnostic test accuracy studies

K Więckowski, T Gallina, A Surdacki… - Journal of clinical …, 2021 - mdpi.com
Coronary artery disease is a global challenge for healthcare systems. Early diagnosis is a
key issue to improve quality of life and reduce morbidity and mortality. Diagonal earlobe …

[HTML][HTML] Endothelial dysfunction: a contributor to adverse cardiovascular remodeling and heart failure development in type 2 diabetes beyond accelerated …

A Gamrat, MA Surdacki, B Chyrchel… - Journal of Clinical …, 2020 - mdpi.com
Endothelial dysfunction, associated with depressed nitric oxide (NO) bioavailability, is a well-
recognized contributor to both accelerated atherogenesis and microvascular complications …

Association of plasma miR-223 and platelet reactivity in patients with coronary artery disease on dual antiplatelet therapy: A preliminary report

B Chyrchel, J Totoń-Żurańska, O Kruszelnicka… - Platelets, 2015 - Taylor & Francis
Decreased plasma levels of microRNA-223 (miR-223), predominantly of platelet origin, were
proposed as a surrogate marker of efficacy of antiplatelet therapy. However, higher on …

[HTML][HTML] Depressed cardiac mechanical energetic efficiency: a contributor to cardiovascular risk in common metabolic diseases—from mechanisms to clinical …

A Juszczyk, K Jankowska, B Zawiślak… - Journal of clinical …, 2020 - mdpi.com
Cardiac mechanical energetic efficiency is the ratio of external work (EW) to the total energy
consumption. EW performed by the left ventricle (LV) during a single beat is represented by …

[HTML][HTML] Platelet reactivity and circulating platelet-derived microvesicles are differently affected by P2Y12 receptor antagonists

B Chyrchel, A Drożdż, D Długosz… - … journal of medical …, 2019 - ncbi.nlm.nih.gov
Background: Platelet-derived microvesicles (PMVs), shed from platelet surface membranes,
constitute the majority of circulating microvesicles and have been implicated in …

Differential associations of circulating asymmetric dimethylarginine and cell adhesion molecules with metformin use in patients with type 2 diabetes mellitus and stable …

O Kruszelnicka, B Chyrchel, A Golay, A Surdacki - Amino acids, 2015 - Springer
Metformin, the drug of first choice in type 2 diabetes mellitus (T2DM), reduces cardiovascular
(CV) morbidity and mortality in part independently of improved glycemic control and …

[HTML][HTML] Association of ADP-induced whole-blood platelet aggregation with serum low-density lipoprotein cholesterol in patients with coronary artery disease when …

B Chyrchel, O Kruszelnicka… - Journal of Clinical …, 2023 - mdpi.com
The degree of platelet inhibition in patients undergoing dual antiplatelet therapy (DAPT)
affects cardiovascular outcomes after acute coronary syndromes (ACS) and/or percutaneous …

[HTML][HTML] Opposite associations of plasma homoarginine and ornithine with arginine in healthy children and adolescents

A JaŸwińska-Kozuba, J Martens-Lobenhoffer… - International journal of …, 2013 - mdpi.com
Homoarginine, a non-proteinogenic amino acid, is formed when lysine replaces ornithine in
reactions catalyzed by hepatic urea cycle enzymes or lysine substitutes for glycine as a …

[HTML][HTML] Thyroid hormones—An underestimated player in dilated cardiomyopathy?

K Zawadzka, R Dziedzic, A Surdacki… - Journal of Clinical …, 2021 - mdpi.com
Dilated cardiomyopathy (DCM) is the most prevalent cardiomyopathy, typified by left
ventricular dilation and systolic dysfunction. Many patients with DCM have altered thyroid …

[HTML][HTML] Diagnostic Ability of Peguero-Lo Presti Electrocardiographic Left Ventricular Hypertrophy Criterion in Severe Aortic Stenosis

A Gamrat, K Trojanowicz, MA Surdacki… - Journal of Clinical …, 2021 - mdpi.com
Traditional electrocardiographic (ECG) criteria for left ventricular hypertrophy (LVH),
introduced in the pre-echocardiographic era of diagnosis, have a relatively low sensitivity …