Hydroxyurea for secondary stroke prevention in children with sickle cell anemia in Nigeria: a randomized controlled trial

SU Abdullahi, S Sunusi, MS Abba, S Sani, HA Inuwa… - Blood, 2023 - ashpublications.org
We tested the hypothesis that fixed oral moderate-dose hydroxyurea (20 mg/kg per day) for
initial treatment of secondary stroke prevention results in an 80% relative risk reduction of …

Primary prevention of stroke in children with sickle cell anemia in sub-Saharan Africa: rationale and design of phase III randomized clinical trial

SU Abdullahi, BJ Wudil, H Bello-Manga… - Pediatric hematology …, 2020 - Taylor & Francis
Strokes in children with sickle cell anemia (SCA) are associated with significant morbidity
and premature death. Primary stroke prevention in children with SCA involves screening for …

Socio-demographic and adherence factors associated with viral load suppression in HIV-infected adults initiating therapy in northern Nigeria: a randomized controlled …

M Coker, MA Etiebet, H Chang, G Awwal… - Current HIV …, 2015 - ingentaconnect.com
Background: Virological suppression is the main goal of antiretroviral therapy. To achieve
this goal, efficient interventions that promote treatment adherence are needed. This study …

[HTML][HTML] Establishing sickle cell disease stroke prevention teams in Africa is feasible: program evaluation using the RE-AIM framework

DL Ghafuri, SU Abdullahi, AH Dambatta… - Journal of pediatric …, 2022 - journals.lww.com
Abstract We used the Reach, Effectiveness, Adoption, Implementation, and Maintenance
(RE-AIM) framework to evaluate a Stroke Prevention Team's readiness to prevent strokes in …

Barriers and Facilitators of Premarital Genetic Counseling for Sickle Cell Disease in Northern Nigeria

AA Galadanci, JH Estepp, H Khan… - Journal of Pediatric …, 2023 - journals.lww.com
In high-income countries, premarital genetic counseling for Sickle Cell Disease (SCD) is a
standard practice. However, in Nigeria, there is no formal premarital genetic counseling …

[HTML][HTML] World Health Organization's Growth Reference Overestimates the Prevalence of Severe Malnutrition in Children with Sickle Cell Anemia in Africa

DL Ghafuri, SU Abdullahi, BW Jibir, S Gambo… - Journal of Clinical …, 2020 - mdpi.com
Anthropometric indices are widely used to assess the health and nutritional status of
children. We tested the hypothesis that the 2007 World Health Organization (WHO) …

Sickle Cell Disease Genomics of Africa (SickleGenAfrica) Network: ethical framework and initial qualitative findings from community engagement in Ghana, Nigeria …

KA Anie, E Olayemi, V Paintsil, E Owusu-Dabo… - BMJ open, 2021 - bmjopen.bmj.com
Objectives To provide lay information about genetics and sickle cell disease (SCD) and to
identify and address ethical issues concerning the Sickle Cell Disease Genomics of Africa …

[HTML][HTML] Capacity building for primary stroke prevention teams in children living with sickle cell anemia in Africa

DL Ghafuri, BC Greene, B Musa, A Gambo, A Sani… - Pediatric …, 2021 - Elsevier
Background Nigeria has the highest proportion of children with sickle cell anemia (SCA)
globally; an estimated 150,000 infants with SCA are born annually. Primary stroke …

[HTML][HTML] Randomized controlled trial of fixed low-vs moderate-dose hydroxyurea for primary stroke prevention in Sub-Saharan Africa: final results of the Spring Trial

SU Abdullahi, BW Jibir, H Bello-Manga, S Gambo… - Blood, 2020 - Elsevier
Introduction: In children with sickle cell anemia (SCA) without transcranial Doppler (TCD)
screening, the incidence rates of ischemic strokes is approximately the same among …

[HTML][HTML] Knowledge and Perception of Religious Leaders on Premarital Genetic Counseling for Sickle Cell Disease in Kano, Northern Nigeria

AA Galadanci, UA Ibrahim, ZL Farouk… - Nigerian Journal of …, 2023 - journals.lww.com
Aims: To assess the knowledge and perception of premarital genetic counseling for sickle
cell disease (SCD) among religious leaders in a culturally and religiously sensitive …