Catalytic generation of N2O3 by the concerted nitrite reductase and anhydrase activity of hemoglobin
S Basu, R Grubina, J Huang, J Conradie… - Nature chemical …, 2007 - nature.com
Nitrite reacts with deoxyhemoglobin to form nitric oxide (NO) and methemoglobin. Though
this reaction is experimentally associated with NO generation and vasodilation, kinetic …
this reaction is experimentally associated with NO generation and vasodilation, kinetic …
Hemoglobin mediated nitrite activation of soluble guanylyl cyclase
Nitrite has long been known to be vasoactive when present at large concentrations but it
was thought to be inactive under physiological conditions. Surprisingly, we have recently …
was thought to be inactive under physiological conditions. Surprisingly, we have recently …
[HTML][HTML] Risk and protective genetic variants in suicidal behaviour: association with SLC1A2, SLC1A3, 5-HTR1B & NTRK2 polymorphisms
TM Murphy, M Ryan, T Foster, C Kelly… - Behavioral and Brain …, 2011 - Springer
Background Suicidal behaviour is known to aggregate in families. Patients with psychiatric
disorders are at higher risk for suicide attempts (SA), however protective and risk genetic …
disorders are at higher risk for suicide attempts (SA), however protective and risk genetic …
Genetic variation in DNMT3B and increased global DNA methylation is associated with suicide attempts in psychiatric patients
Recently, a significant epigenetic component in the pathology of suicide has been realized.
Here we investigate candidate functional SNPs in epigenetic‐regulatory genes, DNMT1 and …
Here we investigate candidate functional SNPs in epigenetic‐regulatory genes, DNMT1 and …
Rate of nitric oxide scavenging by hemoglobin bound to haptoglobin
Cell-free hemoglobin, released from the red cell, may play a major role in regulating the
bioavailability of nitric oxide. The abundant serum protein haptoglobin, rapidly binds to free …
bioavailability of nitric oxide. The abundant serum protein haptoglobin, rapidly binds to free …
Computation of plasma hemoglobin nitric oxide scavenging in hemolytic anemias
A Jeffers, MT Gladwin, DB Kim-Shapiro - Free Radical Biology and …, 2006 - Elsevier
Intravascular hemoglobin limits the amount of endothelial-derived nitric oxide (NO) available
for vasodilation. Cell-free hemoglobin scavenges NO more efficiently than red blood cell …
for vasodilation. Cell-free hemoglobin scavenges NO more efficiently than red blood cell …
Investigating the relationship between childhood sexual abuse, self-harm repetition and suicidal intent: mixed-methods study
BackgroundResearch into the association between childhood sexual abuse (CSA) and self-
harm repetition is limited. AimsWe aimed to examine the association between self-harm …
harm repetition is limited. AimsWe aimed to examine the association between self-harm …
[HTML][HTML] Physical and mental illness comorbidity among individuals with frequent self-harm episodes: a mixed-methods study
Background Research has indicated an increased risk of self-harm repetition and suicide
among individuals with frequent self-harm episodes. Co-occurring physical and mental …
among individuals with frequent self-harm episodes. Co-occurring physical and mental …
Substance use and self-harm emergency department presentations during COVID19: evidence from a National Clinical Programme for Self-Harm
E Maguire, K Kavalidou, N Bannan… - Irish journal of …, 2023 - cambridge.org
Introduction: Given the evidence that drinking patterns and self-harm hospital presentations
have changed during COVID-19, this study aimed to examine any change in self-harm and …
have changed during COVID-19, this study aimed to examine any change in self-harm and …
Fatness, digestion and food of Passamaquoddy young herring
HI Battle, AG Huntsman, AM Jeffers… - Journal of the …, 1936 - cdnsciencepub.com
Using condition factor as criterion of fatness, investigation confirms the report of those
handling them that herring are characteristically fat in each locality of the Passamaquoddy …
handling them that herring are characteristically fat in each locality of the Passamaquoddy …