Background Infliximab and ciclosporin are of similar efficacy in treating acute severe
ulcerative colitis, but there has been no comparative evaluation of their relative clinical …

Background The efficacy of infliximab and ciclosporin in treating severe ulcerative colitis
(UC) is proven, but there has been no comparative evaluation of effectiveness. Objective To …

Introduction Many patients with ulcerative colitis (UC) present with acute exacerbations
needing hospital admission. Treatment includes intravenous steroids but up to 40% of …

Objectives To explore paramedics' experience of delivering fascia iliaca compartment block
(FICB) to patients with suspected hip fracture at the scene of injury. Design Focus groups …

Background A nested qualitative interview study within the CONSTRUCT trial was
conducted to explore experiences and perceptions of patients with acute severe ulcerative …

Background In managing hip fracture, effective pain relief before admission to hospital is
difficult without risking side effects. Although emergency departments routinely use fascia …

Objectives To develop a tool for the accurate reporting and aggregation of findings from
each of the multiple methods used in a complex evaluation in an unbiased way. Study …

Objective To explore patients' experience of receiving pain relief injection for suspected hip
fracture from paramedics at the location of the injury. Design Qualitative interviews within a …

Objective To identify the features and effects of a pathway for emergency assessment and
referral of patients with suspected transient ischaemic attack (TIA) in order to avoid …

Background Adequate pain relief at the point of injury and during transport to hospital is a
major challenge in all acute traumas, especially for those with hip fractures, whose injuries …