Objective To investigate whether discrepancies in trials of use of bone marrow stem cells in
patients with heart disease account for the variation in reported effect size in improvement of …

Aims This meta-analysis aims to quantify the association of reduced coronary flow with all-
cause mortality and major adverse cardiovascular events (MACE) across a broad range of …

Background: Ischemic heart disease (IHD) has been considered the top cause of mortality
globally. However, countries differ in their rates and there have been changes over time …

The adverse consequences of stable coronary artery disease (CAD) are death, myocardial
infarction (MI) and angina. Trials in stable CAD show that percutaneous coronary …

N-of-1 Trial of a Statin, Placebo, or No Treatment Patients who had discontinued statins
because of side effects received four bottles of a statin, four bottles of placebo, and four …

Background Percutaneous coronary intervention (PCI) is frequently performed to reduce the
symptoms of stable angina. Whether PCI relieves angina more than a placebo procedure in …

Background Most people who begin statins abandon them, most commonly because of side
effects. Objectives The purpose of this study was to assess daily symptom scores on statin …

Background Ischaemic heart disease (IHD) is the leading cause of death worldwide and its
prevention is a public health priority. Method We analysed worldwide IHD mortality data from …

Background: In patients presenting with ST-segment–elevation myocardial infarction,
percutaneous coronary intervention (PCI) reduces mortality when compared with fibrinolysis …

Objective 30 mm Hg drops in office systolic blood pressure are reported in trials of renal
denervation, but ambulatory reductions are much smaller. This disparity is assumed to have …