Estimation of absolute risk from nested case-control data

Biometrics. 1997 Jun;53(2):767-74.

Abstract

Benichou and Gail (1995, Biometrics 51, 182-194) describe methods for estimating the absolute risk of developing disease given a set of covariate values over a specified time interval from a case-control study within a cohort. The methods are most suitable for unmatched case-control studies, and are restricted to categorical covariates. Expanding on methods for estimating relative mortality from nested case-control studies presented in Borgan and Langholz (1993, Biometrics 49, 593-602), we present methods for estimating absolute risk from individually matched nested case-control data. These methods accommodate continuous and time-dependent covariate histories, the sampling of cases, and various control sampling designs.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Biometry / methods*
  • Case-Control Studies*
  • Cohort Studies
  • Colorado / epidemiology
  • Data Interpretation, Statistical
  • Humans
  • Lung Neoplasms / etiology
  • Lung Neoplasms / mortality
  • Male
  • Middle Aged
  • Mining
  • Neoplasms, Radiation-Induced / etiology
  • Neoplasms, Radiation-Induced / mortality
  • Occupational Diseases / etiology
  • Occupational Diseases / mortality
  • Occupational Exposure
  • Proportional Hazards Models
  • Radon / adverse effects
  • Risk*
  • Uranium / adverse effects

Substances

  • Uranium
  • Radon